Sökning: "Tasnim Dayeh"

Hittade 1 avhandling innehållade orden Tasnim Dayeh.

1. 1. The Human Pancreatic Islet Methylome and Its Role in Type 2 Diabetes

   Författare :Tasnim Dayeh; Diabetes - epigenetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CpG-SNP; glucagon secretion; insulin secretion; human pancreatic islets; DNA methylation; Epigenetics;

   Sammanfattning : Islet dysfunction is central to the development and progression of type 2 diabetes (T2D). Epigenetic modifications are essential for establishing and maintaining cell identity and function in normal circumstances. Exposure to adverse environmental factors may alter the epigenome, and result in changes of gene expression and the resulting phenotype. LÄS MER