Sökning: "Tamoxifen"

Visar resultat 6 - 10 av 99 avhandlingar innehållade ordet Tamoxifen.

  1. 6. Effects of sex steroids and tamoxifen on matrix metalloproteinase activity and generation of endostatin in the breast

    Författare :Ulrika W. Nilsson; Charlotta Dabrosin; Lena Claesson-Welsh; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Angiogenesis; Breast cancer; TGF-β1; Endostatin; Estradiol; Mammary gland; Matrix metalloproteinases; MCF-7; Microdialysis; Nude mice; Tamoxifen; Oncology; Onkologi;

    Sammanfattning : Sex steroids are inevitable in women. However, long-term exposure to sex steroids increases the risk of breast cancer. A complete understanding of sex steroid control of the breast and how it relates to breast cancer risk is still lacking. LÄS MER

  2. 7. The effects of flaxseed and tamoxifen on the inflammatory microenvironment in normal breast tissue and in breast cancer

    Författare :Gabriel Lindahl; Charlotta Dabrosin; Signe Borquist; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breast cancer; inflammation; chemoprevention; tamoxifen; phytoestrogens; flaxseed; enterolactone; interleukins; osteopontin; chemokines; matrix metalloproteases; microdialysis;

    Sammanfattning : Breast cancer is the most common cancer among women worldwide today. Nearly 9000 women are diagnosed with breast cancer in Sweden yearly and despite advantages in diagnostics and treatments approximately 1400 women still die from their disease every year. LÄS MER

  3. 8. Prognostic and Predictive Markers in Primary Breast Cancer - Quality Assurance and Long-term Effects of Adjuvant tamoxifen Treatment

    Författare :Maria Ekholm; Bröstcancer-genetik; []
    Nyckelord :Breast cancer; Quality assurance; Tamoxifen; Long-term effects;

    Sammanfattning : .... LÄS MER

  4. 9. Homeobox B13 in breast cancer : Prediction of tamoxifen benefit

    Författare :Piiha-Lotta Jerevall; Olle Stål; Agneta Jansson; Håkan Hedman; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : A major issue in the management of breast cancer is to identify patients who are less likely to be cured after primary treatment and would benefit from adjuvant chemotherapy. Of great importance is also identification of patients with only local disease who traditionally would be given chemotherapy but would survive without. LÄS MER

  5. 10. The role of the androgen receptor and hydroxysteroid 17β dehydrogenase in breast cancer : Impact on tamoxifen treatment

    Författare :Erik Hilborn; Agneta Jansson; Olle Stål; Yvonne Ceder; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The healthy breast is a tissue composed of centrally located milk producing glands connected to the nipple by ducts, surrounded by fat tissue and connective tissue. The growth of the breast is primarily mediated by the estrogens, while the androgens mediate tissue homeostasis and protect against growth signals. LÄS MER