Sökning: "Tamoxifen"
Visar resultat 16 - 20 av 99 avhandlingar innehållade ordet Tamoxifen.
16. GPR30 in breast cancer - from molecular mechanisms to clinical outcome
Sammanfattning : .... LÄS MER
17. Tamoxifen response in primary breast cancer with special reference to tumour-specific VEGF-A and VEGFR2
Sammanfattning : Background: Treatment of primary breast cancer is individualised and adjuvant systemic treatment is delivered to most patients after surgery. Oestrogen receptor (ER) status and progesterone receptor status (PR) can define patients who would benefit from adjuvant endocrine therapy with tamoxifen (TAM) alone or as chemo-endocrine therapy. LÄS MER
18. Customization of tamoxifen therapy : not only a dream
Sammanfattning : Breast cancer (BC) is the most common form of cancer in western women. The grand majority of the afflicted women are eligible for endocrine treatment. Tamoxifen has been the golden standard treatment for more than three decades. Unfortunately, resistance towards this drug is a major concern in the clinic. LÄS MER
19. TISSUE MICROARRAY PERSPECTIVES ON CYCLIN D1 IN BREAST CANCER: Progression, prognosis and prediction
Sammanfattning : Breast cancer is a truly heterogenous disease, reflected in the existence of a wide spectrum of phenotypic subsets of tumours with varying intrinsic aggressiveness as well as ability to respond to a given treatment. Recent advances in large-scale genomic and proteomic screening techniques have confirmed this heterogeneity also at a molecular level, but there is still a bottleneck to be overcome before the discoveries in the laboratory can be translated into the much more complex clinical situation in order to develop better targeted therapies. LÄS MER
20. Erythropoietin receptor in growth control and anti-estrogen resistance of estrogen receptor positive breast cancer
Sammanfattning : The main function of Erythropoietin (EPO) and its receptor (EPOR) is the stimulation of erythropoiesis. Therefore, recombinant human EPO (rhEPO) is used to treat anemia in cancer patients, but some studies have reported that rhEPO treatment might promote tumor progression. Additionally, EPOR expression has been detected in various cancer forms. LÄS MER