Sökning: "TTR"
Visar resultat 1 - 5 av 51 avhandlingar innehållade ordet TTR.
1. Selection of transthyretin amyloid inhibitors
Sammanfattning : Amyloidosis is a group of clinical disorders caused by the aggregation of specific proteins into abnormal extracellular deposits. Today, 31 different proteins have been linked to amyloid diseases including transthyretin-related amyloidosis (ATTR). LÄS MER
2. Enthymemes in Dialogue: A micro-rhetorical approach
Sammanfattning : In dialogue we frequently present arguments which are based on commonly accepted non-logical inferences. In rhetorical theory, this type of argument is called an enthymeme, and a pattern of reasoning that it is based on is called a topos. The main purpose of this thesis is to investigate the role that enthymemes play in natural language dialogue. LÄS MER
3. Anticoagulation treatment in patients with a mechanical heart valve
Sammanfattning : BackgroundEvery year about 2,500 patients in Sweden undergo surgery for heart valve disease, primarily in the aortic valve. In contrast to the mitral valve, which can be repaired in 70% of the cases, the aortic valve is normally replaced by a mechanical or biological prosthesis. LÄS MER
4. Warfarin treatment quality in stroke prevention
Sammanfattning : BackgroundIschemic stroke is a serious condition often associated to presence of atrial fibrillation (AF). Use of anticoagulants for AF patients greatly reduces the risk of stroke. Warfarin is the most commonly used anticoagulant in Sweden. The aim of this thesis was to study the impact of warfarin treatment quality in Swedish stroke prevention. LÄS MER
5. Molecular Aspects of Transthyretin Amyloid Disease
Sammanfattning : This thesis was made to get a deeper understanding of how chaperones interact with unstable, aggregation prone, misfolded proteins involved in human disease. Over the last two decades, there has been much focus on misfolding diseases within the fields of biochemistry and molecular biotechnology research. LÄS MER