Sökning: "TSTA"
Hittade 3 avhandlingar innehållade ordet TSTA.
1. TARP Promoter-Based Prostate Cancer Gene Therapy : From Development to Application
Sammanfattning : Prostate cancer is one leading cause of cancer-related death among men in Western countries. The standard therapies for localized prostate cancer include radical prostatectomy and radiation therapy. Such measures are relatively effective in the short term, but many patients ultimately relapse. LÄS MER
2. Adenovirus-mediated CD40 Ligand Immunotherapy of Prostate and Bladder Cancer
Sammanfattning : Cancer immunotherapy aims at reversing the immunosuppressive tumor environment and enhancing anti-tumor immunity. This thesis comprises studies on murine models for prostate (TRAMP-C2) and bladder (MB49) cancer with the aim to explore if the introduction of an adenoviral vector expressing CD40 ligand (AdCD40L) can induce anti-tumor immune responses. LÄS MER
3. Persistence of polyomavirus : versus immunity to polyoma tumors
Sammanfattning : The aim of this thesis was to understand the role of different specific immune effectors with regard to polyomavirus persistence and polyomavirus induced tumor development. Furthermore, an MHC class I restricted short viral peptide was identified as a target for polyomavirus specific recognition of polyoma tumor cells. LÄS MER