Sökning: "TRAMP mice"

Hittade 2 avhandlingar innehållade orden TRAMP mice.

1. 1. Phytoestrogens and prostate cancer : experimental, clinical, and epidemiological studies

   Författare :Annika Bylund; Pär Stattiin; Anders Bergh; Göran Hallmans; Swen-Olof Andersson; Umeå universitet; []
   Nyckelord :prostatic neoplasm; phytoestrogens; lignans; enterolactone; rye; 7-hydroxymataireorcinol; nude mice; TRAMP mice; nested case control study; LNCaP; Oncology; onkologi;

   Sammanfattning : Dietary factors may affect development and progression of prostate cancer. Experimental and epidemiological studies have suggested an effect of phytoestrogens on prostate cancer. Lignans are the predominant phytoestrogen in a Western diet. LÄS MER

3. 2. Adenovirus-mediated CD40 Ligand Immunotherapy of Prostate and Bladder Cancer

   Författare :Helena Dzojic; Magnus Essand; Thomas H Tötterman; Aristides Eliopoulos; Uppsala universitet; []
   Nyckelord :Medicine; immunotherapy; gene therapy; prostate cancer; bladder cancer; adenoviral vector; CD40 ligand; promoter; PPT; TSTA; depsipeptide FK228; TRAMP-C2; Medicin;

   Sammanfattning : Cancer immunotherapy aims at reversing the immunosuppressive tumor environment and enhancing anti-tumor immunity. This thesis comprises studies on murine models for prostate (TRAMP-C2) and bladder (MB49) cancer with the aim to explore if the introduction of an adenoviral vector expressing CD40 ligand (AdCD40L) can induce anti-tumor immune responses. LÄS MER