Sökning: "TOF"

Visar resultat 1 - 5 av 194 avhandlingar innehållade ordet TOF.

  1. 1. Single fluid inclusion analysis using ToF-SIMS : Implications for ancient Earth biodiversiy and paleoenvironment studies

    Författare :Sandra Siljeström; Jukka Lausmaa; Andrew Steele; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ToF-SIMS; time-of-flight secondary ion mass spectrometry; fluid inclusions; biomarkers; hopanes; steranes; early life; paleoenvironment; oil; eukaryotes; Earth sciences; Geovetenskap; geokemi; Geochemistry;

    Sammanfattning : When and how life first emerged on the Earth is an area of intense research. Signs of the first life on Earth, including morphological fossils, are scarce and hard to interpret. An alternative approach is to study organic biomarkers, which are molecular fossils commonly considered as bona fide biosignatures. LÄS MER

  3. 2. Electronic excitation, luminescence and particle emission : Studying ion-induced phenomena in ToF-MEIS

    Författare :Svenja Lohmann; Daniel Primetzhofer; Friedrich Aumayr; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TOF-MEIS; ion beam analysis; deep UV; desorption; electronic sputtering; TiN;

    Sammanfattning : Medium energy ion scattering (MEIS) is an experimental technique for the high-resolution depth profiling of thin films. Commonly, ions with energies between several ten to a few hundred keV are employed as probes, and backscattered particles are detected. LÄS MER

  4. 3. Application of imaging TOF-SIMS in cell and tissue research

    Författare :Katrin Richter; Göteborgs universitet; []
    Nyckelord :TOF-SIMS; imaging mass spectrometry; cryopreparation; ions; lipids; galactosylceramide; sulfatide; fatty acids;

    Sammanfattning : This thesis is aimed at extending the use of TOF-SIMS (time of flight secondary ion mass spectrometry) as an analytical tool in cell and tissue research. TOF-SIMS is a relatively new method that allows analysis of the chemical composition of sample surfaces. LÄS MER

  5. 4. Identification and imaging of lipids in tissues using TOF-SIMS

    Författare :Ylva Magnusson; Göteborgs universitet; []
    Nyckelord :mass spectrometry; lipids; fatty acids; diacylglycerols; triacylglycerols; TOF-SIMS; adipose tissue; aortic wall; skeletal muscle; obesity; principal component analysis;

    Sammanfattning : Introduction: Normal lipid metabolism in the adipose tissue, skeletal muscle and aortic wall is important for the physiological function of these tissues. Dyslipidemia that is often associated with intake of high energy diet and sedentary lifestyles can lead to the development of insulin resistance and cardiovascular diseases. LÄS MER

  7. 5. Analysis of Metabolites in Complex Biological Samples Using LC/MS and Multivariate Data Analysis : Metabolic Fingerprinting and Detection of Biomarkers

    Författare :Helena Idborg; Sven Jacobsson; Per-Olof Edlund; Jonas Bergquist; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Metabolomics; Metabonomics; Metabolic Fingerprinting; Drug Metabolism; Biomarkers; Human Plasma; Rat Urine; LC MS; ZIC-HILIC; UPLC; UHPLC; ToF; Curve Resolution; Peak Detection; Pattern Recognition; Classification; PCA; PLS; PARAFAC; N-PLS; Data Fusion; Hierarchical Modeling; Batch modeling; Data Concatenation; Breast Cancer; Phospholipidosis; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Sammanfattning : To facilitate early diagnosis of diseases and elucidation of the processes involved in their development and progression, various specific compounds or ‘biomarkers’ are often monitored. The first step is to decide which compounds to analyze. LÄS MER