Sökning: "TNFR2"

Hittade 5 avhandlingar innehållade ordet TNFR2.

  1. 1. The involvement of the TNF-alpha system in skeletal muscle in response to marked overuse

    Författare :Lina Renström; Sture Forsgren; Per Stål; Håkan Alfredson; Eva Ekblad; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TNF-alpha; TNFR1; TNFR2; muscle damage; myositis; peritendinous tissue; tendinopathy;

    Sammanfattning : Painful conditions having the origin within the musculoskeletal system is a common cause for people to seek medical care. Between 20-40% of all visits to the primal care in Sweden are coupled to pain from the musculoskeletal system. Muscle pain and impaired muscle function can be caused by muscles being repetitively overused and/or via heavy load. LÄS MER

  2. 2. TNF-α and neurotrophins in Achilles tendinosis

    Författare :Johan Bagge; Sture Forsgren; Tomas Movin; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Achilles tendon; tendinosis; tendinopathy; neurotrophins; TNF-alpha; physical acitivity; apoptosis; proliferation; pain; remodelling; anatomi; Human Anatomy;

    Sammanfattning : Tenocytes are the principal cells of the human Achilles tendon. In tendinosis, changes in the metabolism and morphology of these cells occur. Neurotrophins are growth factors essential for the development of the nervous system. LÄS MER

  3. 3. Periodontal medicine : oral inflammatory conditions with special emphasis on immunological aspects

    Författare :Jeneen Panezai; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Systemic effects of periodontal disease have been a subject of interest for the past century, with intense focus converging since the past decade. Both rheumatoid arthritis (RA) and periodontal disease (PD) are immuno-inflammatory diseases with osteolysis as its hallmark feature. Activated T cells are known to modulate osteoclastogenesis. LÄS MER

  4. 4. Studies on Redox-proteins and Cytokines in inflammation and Cancer

    Författare :Akter Hossain; Anders Rosén; Christer Lindqvist; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Thioredoxin Trx ; Selenium; Tumor necrosis factor TNF ; Cancer; nflammation; oxidative stress; Protein-disulfide isomerase PDI ; Tumor necrosis factor receptor TNFR ; Medical cell biology; Medicinsk cellbiologi;

    Sammanfattning : The redox state in the cell plays a major role in determining vital functions and its major imbalance can lead to severe cell injury or death. Redox active proteins and cytokines involved in this process includes thioredoxin (Trx), protein disulfide isomerase (PDI), and tumor necrosis factor (TNF) superfamilies. LÄS MER

  5. 5. Organic dust-induced signaling in human pulmonary epithelial cells : emphasis on effects of cAMP modulation

    Författare :Karin Burvall; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : To study signaling transductions in innate immunity a model system was applied where A549 alveolar epithelial type II cells were used as target and organic dust collected in swine confinement buildings as stimulus. The dust represents a complex mixture of feed and faecal particles, dander from swine, bacteria (whole bacteria and cell wall components) and fungi. LÄS MER