Sökning: "TIMP- 3"

Visar resultat 21 - 25 av 26 avhandlingar innehållade orden TIMP- 3.

  1. 21. Immune regulation in multiple sclerosis : cytokines and metalloproteinases

    Författare :Volkan Özenci; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Immunological mechanisms play a central role in the pathogenesis sclerosis (MS). In this study two groups of related immune variables are cytokines and metalloproteinases (MMPs), which regulate each other's production and activation. LÄS MER

  3. 22. Treatment of subacromial pain and rotator cuff tears

    Författare :Hanna Cecilia Björnsson Hallgren; Lars Adolfsson; Kajsa Johansson; Rolf Norlin; Li Tsai-Fällender; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Shoulder; rotator cuff tear; ultrasound; surgery; exercises;

    Sammanfattning : Shoulder pain is very common, affecting 14-21 % of the population at some time during their lifetime. The aims of this thesis were to improve the understanding of various aspects concerning the pathogenesis and treatment of subacromial pain and rotator cuff tears. LÄS MER

  4. 23. Matrix metalloproteinases in Helicobacter inducedgastritis

    Författare :Philip Bergin; Göteborgs universitet; []
    Nyckelord :Helicobacter pylori; Helicobacter felis; Matrix metalloproteinase; macrophage; ; Gastritis;

    Sammanfattning : Helicobacter pylori infects the stomach and areas of gastric metaplasia in the duodenum. Theinfection leads to peptic ulcers or gastric cancers in 10-20% of infected individuals, while themajority are more or less asymptomatic. However, active chronic gastritis develops in all infectedindividuals, often in association with atrophic gastritis. LÄS MER

  5. 24. Circulating biomarkers in patients with abdominal aortic aneurysm

    Författare :Despina Flondell-Sité; Vaskulära sjukdomar - kliniska studier; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; matrix metalloproteinases; biomarkers; risk factors; fibrinolysis; coagulation; inflammation; Abdominal aortic aneurysm; statin; interleukin 6.; APC-PCI complex; serpine-1; endothelin-1;

    Sammanfattning : Abdominal aortic aneurysm (AAA) develops in 3-6% of the population over 65 years and affects mainly men. AAA has a complex etiology involving inflammation, proteolysis, fibrinolysis and coagulation. LÄS MER

  7. 25. Studies of molecular mechanisms of action of TNF antagonists in rheumatoid arthritis

    Författare :Anca Irinel Catrina; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Rheumatoid arthritis; TNF antagonists; cytokines; macrophages; matrix metalloproteinases; osteoprotegerin; RANKL; apoptosis;

    Sammanfattning : Rheumatoid arthritis (RA) is a common chronic inflammatory disease characterized by progressive bone destruction that leads to joint deformity and physical disability. Even though several therapeutic drugs are available, none have emerged as an ideal RA treatment that delays joint destruction and halts disease progression. LÄS MER