Sökning: "TIMP- 3"

Visar resultat 11 - 15 av 26 avhandlingar innehållade orden TIMP- 3.

  1. 11. Matrix metalloproteinases and their inhibitors in ocular neovascularization

    Författare :Björn Steén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Angiogenesis; Neovascularization; Retina; Bruch membrane; Cornea; MMP; TIMP; VEGF; In situ hybridization.;

    Sammanfattning : Growth of pathological new vessels (angiogenesis) in the eye is a leading cause of severe vision-loss. Ocular angiogenesis is seen in the anterior part of the eye as in corneal neovascularization, or in the posterior part as in diabetic retinopathy, retinopathy of prematurity or age-related macular degeneration. LÄS MER

  3. 12. Cervical ripening : an inflammatory process involving cytokines, metalloproteinases and foetal fibronectin

    Författare :Maria Sennström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :cervical ripening; interleukin-8; interleukin-6; granulocyte colony stimulating factor; metalloproteinase- 1; -3 - and -8; foetal fibronectin;

    Sammanfattning : The aim of the thesis was to identify cytokines, metalloproteinases and foetal fibronectin in human cervical tissue and to investigate if changes are of importance for the final cervical ripening. The human cervical ripening is a prerequisite for a normal start and progress of labour. LÄS MER

  4. 13. Colorectal cancer treatment and early response evaluation : how do we best evaluate treatment response?

    Författare :Per Byström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Colorectal cancer; TIMP-1; tumor marker; PET; CEA; CA19-9; TPA; SAA; CRP; prealbumin; HRQoL;

    Sammanfattning : Colorectal cancer (CRC) is common, being responsible for around 12% of new cancers in Sweden, and contributing heavily to the large numbers of cancer deaths yearly. CRC is the second most common cause of cancer death not only in Sweden but also worldwide. LÄS MER

  5. 14. Inflammation and cortisol response in coronary artery disease

    Författare :Johnny Nijm; Lena Jonasson; Eva Särendahl; Per Tornvall; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Coronary artery disease; Cardiology; Kardiologi; Internal medicine; Invärtesmedicin;

    Sammanfattning : Atherosclerosis is characterized by a chronic inflammation, involving autoimmune components, in the arterial wall. An increase in proinflammatory activity relative to anti-inflammatory activity is considered to cause a progression of the disease towards plaque instability and risk of atherothrombotic events, such as acute coronary syndrome (ACS). LÄS MER

  7. 15. Inflammatory response in periodontal tissue in children with Down syndrome

    Författare :Georgios Tsilingaridis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Periodontal diseases are inflammatory diseases affecting the supporting tissues of the teeth. Subjects with Down syndrome have a higher prevalence of periodontal disease compared to healthy controls. Periodontal disease in Down syndrome is considered to be multifactorial, although the aetiology is uncertain. LÄS MER