Sökning: "TIM molecule"

Hittade 5 avhandlingar innehållade orden TIM molecule.

  1. 1. Ligation-mediated Molecular Analysis of Influenza Subtypes, Splicing and Protein Glycosylation

    Författare :Tim Conze; Ulf Landegren; Mats Nilsson; Ola Söderberg; Jörn Glökler; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ligase; proximity ligation; gastric cancer; glycosylation; alternative splicing; avian influenza; padlock probe; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Binder-based assays are employed throughout the life sciences. Powerful signal amplification techniques have enabled detection of very rare molecule species diluted in simple buffers. Unspecific binding of primary binders leads to increased background in more complex samples. LÄS MER

  3. 2. Neurotrophic and immune regulatory factors in neuroinflammation

    Författare :Alexander W Gielen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Neurotrophins; EAE; MS; TIM; Neuroprotection;

    Sammanfattning : Inflammatory reactions in the nervous system act as a double-edged sword. On the one hand, neuroinflammation can have very devastating effects on the nervous system, leading to neurological dysfunction. LÄS MER

  4. 3. Immune responses in defined subgroups of patients with pulmonary sarcoidosis

    Författare :Farah Idali; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Sarcoidosis; Löfgren s syndrome; cytokine; regulatory T cell; TIM molecule; TLR;

    Sammanfattning : This thesis focuses on inflammatory responses in the airways of sarcoidosis patients. Sarcoidosis is a T helper 1-mediated inflammatory disease with unknown aetiology. HLA-DRB1*0301pos sarcoidosis patients often present with an acute form of disease, i.e. LÄS MER

  5. 4. Intestinal ischemia and reperfusion. Proinflammatory response and organ dysfunction

    Författare :Knut Olanders; Lund Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; traumatology; Kirurgi; ortopedi; traumatologi; orthopaedics; Surgery; inflammation; cytokine; leukocyte; reperfusion; ischemia; permeability; Intestine; endothelium;

    Sammanfattning : Intestinal I/R is considered to be an important initiating event in several pathophysiological conditions such as trauma, bleeding, sepsis and pancreatitis, frequently leading to concomitant both single and potentially multiple organ dysfunction. The purpose of this thesis was to study mechanims underlying the development of multiple organ dysfunction, with special focus on intercellular proinflammatory regulation in the concurrent development of tissue injury. LÄS MER

  7. 5. MAIT cells in placental tissues and their reconstitution following allogeneic hematopoietic stem cell transplantation

    Författare :Martin Solders; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The placenta is a temporary organ of human reproduction. Both the fetus and placenta are covered in a membrane of maternal origin, the decidua. After the 1st trimester, the fetus is supplied with oxygen and nutrients by maternal arterial blood that penetrates the decidua and fills the intervillous space of the placenta. LÄS MER