Sökning: "TGFbeta signal transduction"

Hittade 1 avhandling innehållade orden TGFbeta signal transduction.

1. 1. TRAF6 stimulates TGFβ-induced oncogenic signal transduction in cancer cells

   Författare :Shyam Kumar Gudey; Marene Landström; Urban Lendahl; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; c-Jun; invasion; non-Smad; Notch; NICD; oncogenesis; presenilin1; PKCζ; prostate cancer; p21; p38; p300; Snail1; TGFβ; TβRI; TACE; TRAF6; ubiquitination; TGFbeta signal transduction; Pathology; patologi;

   Sammanfattning : Prostate cancer is one of the leading causes of cancer-related deaths in men worldwide, with 10,000 new cases/year diagnosed in Sweden. In this context, there is an urgent need to identify new biomarkers to detect prostate cancer at an initial stage for earlier treatment intervention. LÄS MER