Sökning: "TGF-β3"

Hittade 4 avhandlingar innehållade ordet TGF-β3.

  1. 1. Production of neocartilage tissues using primary chondrocytes

    Författare :Janne Ylärinne; Mikko Lammi; Chengjuan Qu; Mats Brittberg; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; primary chondrocytes; articular cartilage; tissue engineering; neocartilage; scaffold; scaffold-free; hyaluronan; self-assembling peptide; TGF-β3; glucosamine sulfate; hypoxia; hypertonic medium; glucose;

    Sammanfattning : Hyaline cartilage is a highly specialized tissue, which plays an important role in the articulating joints of an individual. It provides the joints with a nearly frictionless, impact resisting surface to protect the ends of the articulating bones. LÄS MER

  3. 2. Mast Cell Migration in Inflammatory Diseases

    Författare :Niclas Olsson; Gunnar Nilsson; Jaroslaw Dastych; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; Mast cells; chemotaxis; inflammation; Patologi; Pathology; Patologi;

    Sammanfattning : Mast cells (MCs) are forceful multifunctional effector cells of the immune system. MCs are normally distributed throughout connective and mucosal tissues, but in several pathological conditions accumulation of MCs occur. LÄS MER

  4. 3. Keloids - A fibroproliferative disease

    Författare :Oliver Seifert (Bock); Inger Rosdahl; Mona Ståhle; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; keloid; TGF-beta; SMAD; quality of life; Dermatology and venerology; Dermatologi och venerologi;

    Sammanfattning : Keloids are a fibroproliferative disorder of unknown etiology developing in the skin after injury or spontaneously. The aim of this thesis is to gain deeper insight into the role of TGF-β and its signaling pathway proteins, SMADs, in the pathogenesis of keloids and describe the gene expression profile in different keloid sites in the search for potential target genes for future treatment. LÄS MER

  5. 4. Extracellular matrix in atherosclerotic plaques: its role in plaque stability

    Författare :Christoffer Tengryd; Kardiovaskulär forskning - translationella studier; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Extracellular matrix; Laminin; Collagen; Proteoglycans; Atherosclerosis; Carotid plaque; TGF-β;

    Sammanfattning : Atherosclerosis is a systemic disease affecting the large arteries caused by the accumulation of lipids in the vessel wall. Cardiovascular disease due to atherosclerosis is today the most common cause of death globally through its end consequences: myocardial infarctions and stroke. LÄS MER