Sökning: "TFPI-2"

Hittade 3 avhandlingar innehållade ordet TFPI-2.

1. 1. Novel Aspects of the Coagulation System in Host Defence

   Författare :Praveen Papareddy; Lund Dermatologi och venereologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Host defence peptides; Coagulation system; Sepsis; Thrombin; TFPI-1; TFPI-2; HCII;

   Sammanfattning : Bacterial infections are a major global threat to public health and sepsis is a major cause of morbidity and mortality. Sepsis incidence is rising, with supportive treatments and antibiotics being the main treatment possibilities. LÄS MER

3. 2. Novel host defence mechanisms during bacterial infections

   Författare :Malin Elvén; Lund Dermatologi och venereologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ApoE; Complement System; TFPI-2; Antimicrobial peptides; AMP; Immunolgobulins; endotoxins; Staphylococcus aureus; Pseudomonas aeruginosa; Escheria coli;

   Sammanfattning : The immune system has evolved through thousands of years and its architecture has challenged the medical field since the first hieroglyphs and will likely continue do so. With our co-evolution with millions of other species, the complexity to treat infectious diseases has been a race in increasing speed ever since. LÄS MER

4. 3. Targeting bacterial infections by using immunomodulatory host defence peptides and proteins

   Författare :Martina Kalle; Lund Dermatologi och venereologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Host dfence peptides; Sepsis; Immunomodulation; Heparin cofactor II;

   Sammanfattning : Bacterial infections and sepsis are amongst the leading causes of death worldwide. Sepsis is caused by an uncontrolled systemic host response towards an invading pathogen. Due to the engagement of various systems including cellmediated responses, the coagulation and complement cascades, treatment of sepsis remains challenging. LÄS MER