Sökning: "T1DM"

Visar resultat 21 - 25 av 27 avhandlingar innehållade ordet T1DM.

1. 21. Causal inference and case-control studies with applications related to childhood diabetes

   Författare :Emma Persson; Ingeborg Waernbaum; Xavier de Luna; Gisela Dahlquist; Stijn Vansteelandt; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; covariate selection; design-weighted estimation; marginal effect; matching; register study; treatment effect; type 1 diabetes mellitus; Statistics; statistik;

   Sammanfattning : This thesis contributes to the research area of causal inference, where estimation of the effect of a treatment on an outcome of interest is the main objective. Some aspects of the estimation of average causal effects in observational studies in general, and case-control studies in particular, are explored. LÄS MER

3. 22. Fetal and neonatal risk factors for diseases caused by disturbances in the function of the immune system

   Författare :Sara Aspberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Diabetes mellitus; coeliac disease; inflammatory bowel disease; asthma; fetal; neonatal; risk; intrauterine growth; infection; smoking; icterus; phototherapy;

   Sammanfattning : Diseases caused by disturbances in the function of the immune system are a heterogeneous group of disorders, including e g allergic and autoimmune diseases. Several of these diseases have become increasingly common during the last decades. The reasons for this increase in prevalence are mostly unknown. LÄS MER

4. 23. Immunogenetic markers in immune mediated diseases

   Författare :Liene Nikitina-Zake; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :HLA; MICA; TNFA; TNFa; KIR; CIN; cervical cancer; juvenile arthritis; MCTD; type I diabetes mellitus;

   Sammanfattning : The aim of this thesis was to study HLA class II markers, as well as other - MHC and non MHC genes in different immune - mediated diseases, namely, cervical intraepithelial neoplasia (CIN), cervical cancer, juvenile idiopathic arthritis (JIA), mixed connective tissue disease (MCTD) and type I diabetes mellitus (T1 DM). HLA class II genes are located on the short arm of chromosome 6 and are known to be important for pathogenesis of immune-mediated diseases due to the function of the molecules these genes encode. LÄS MER

5. 24. Modeling and Prediction in Diabetes Physiology

   Författare :Marzia Cescon; Institutionen för reglerteknik; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

   Sammanfattning : Diabetes is a group of metabolic diseases characterized by the inability of the organism to autonomously regulate the blood glucose levels. It requires continuing medical care to prevent acute complications and to reduce the risk of long-term complications. LÄS MER

7. 25. Mapping genetic diseases in northern Sweden

   Författare :Elisabet Einarsdottir; Dan Holmberg; Gösta Holmgren; Ulf Gyllensten; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; isolated populations; linkage disequilibrium; linkage analysis; genome-wide scan; hereditary sensory and autonomic neuropathy; type 1 diabetes mellitus; type 2 diabetes mellitus; autoimmune thyroid disease; Genetik; Clinical genetics; Klinisk genetik; medicinsk genetik; Medical Genetics;

   Sammanfattning : The population of northern Sweden has previously been shown to be well suited for the mapping of monogenic diseases. In this thesis we have tested the hypothesis that this population could also be used for efficient identification of risk genes for common diseases. LÄS MER