Sökning: "T-cell recruitment"

Visar resultat 6 - 10 av 73 avhandlingar innehållade orden T-cell recruitment.

1. 6. Humoral and cellular immune response to Helicobacter pylori in Bangladeshi children and adults that may be related to protection

   Författare :Taufiqur Rahman Bhuiyan; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Helicobacter pylori; Adults; Children; Birth cohort; Maternal antibodies; Serology; Th17; T cell; B cell; Developing country;

   Sammanfattning : Helicobacter pylori (Hp) colonizes the human gastric and duodenal mucosa and the infection may cause peptic ulcers and gastric adenocarcinoma. Half of the world’s population is infected with Hp with the highest prevalence in developing countries. LÄS MER

3. 7. Molecular and cellular strategies to enhance efficacy of T cell-based cancer therapy

   Författare :Pascal Dammeyer; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :β2-microglobulin; MHC class I antigen defects; immune escape; heal-inducible; amplifier vector; GM-CSF; tumor immunity; T lymphocytes;

   Sammanfattning : A combined approach of vaccination with β2-microglobulin (β2m)-deficient dendritic cells (DCs) and granulocyte-macrophage colony-stimulating factor (GM-CSF) as a potent adjuvant may link cellular and molecular strategies to further enhance anti-tumor T-cell responses. T lymphocytes can mediate a potent anti-tumor immune response. LÄS MER

4. 8. Effects of Complement Opsonization of HIV on Dendritic Cells : and Implications for the Immune Response

   Författare :Rada Ellegård; Marie Larsson; Jorma Hinkula; Johan D Söderholm; William Paxton; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; HIV; dendritic cells; complement; innate immune response; TLR signaling; T cell activation; NK cells; inflammation; antiviral response; immune evasion;

   Sammanfattning : Dendritic cells are key players during HIV pathogenesis, and shape both the immediate immune response at the site of infection as well as directing the adaptive immune response against the virus. HIV has developed a plethora of immune evasion mechanisms that hijack dendritic cell functions, suppressing their ability to mount an accurate immune response and exploiting them for efficient viral transfer to target T cells. LÄS MER

5. 9. Platelet-lymphocyte cross-talk in atherogenesis : experimental studies on platelet-regulated lymphocyte adhesion and CD4+ T cell activation

   Författare :Zhu Linjing; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Atherosclerosis is an inflammatory and thrombotic disease. Platelets and lymphocytes, especially CD4+ T cells, are indispensable players during the initiation and progression of atherosclerotic lesion formation. During the early stage of atherogenesis, lymphocytes are generally thought to be recruited from arterial blood flow. LÄS MER

7. 10. Adaptive immune response in the intestinal mucosa of microscopic colitis patients

   Författare :Ashok Kumar Kumawat; Elisabeth Hultgren-Hörnquist; Johan Bohr; Curt Tysk; Allan Sirsjö; Samuel Lundin; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microscopic colitis; collagenous colitis; lymphocytic colitis; intraepithelial lymphocytes; lamina propria lymphocytes; T cell receptor excision circle; T helper cells; cytotoxic T lymphocyte and mucosal cytokines; Biomedicin; Biomedicine;

   Sammanfattning : Microscopic colitis (MC) is a chronic diarrhoeal disease of unknown aetiology, comprising collagenous colitis (CC) and lymphocytic colitis (LC). The nature of the adaptive local immune responses in the mucosa of MC patients is however far from elucidated. LÄS MER