Sökning: "T-antigen"

Visar resultat 11 - 15 av 21 avhandlingar innehållade ordet T-antigen.

  1. 11. Development of Real-Time PCR Based Methods for Detection of Viruses and Virus Antibodies

    Författare :Amal Elfaitouri; Jonas Blomberg; Helene Norder; Uppsala universitet; []
    Nyckelord :Microbiology; Real-time PCR; broadly targeted PCR; degenerated PCR; rTth DNA polymerase; thermolabile UNG; QPIA; IgM; Mikrobiologi;

    Sammanfattning : Quantitative real-time PCR (QPCR) technology has been very useful for diagnosis of viral diseases. QPCR has recently reached a level of sensitivity, simplicity, and reproducibility which allows a large number of samples to be screened rapidly, make it a suitable tool for the clinical virology diagnostics. LÄS MER

  3. 12. The cell line RN33B transplanted to adult retina

    Författare :Anita Blixt Wojciechowski; Lund Oftalmologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oftalmologi; host glial response; Ophtalmology; differentiation; migration; proliferation; survival; immunosuppression; RN33B; brain-derived precursor cells; retinal degeneration; subretinal transplantation;

    Sammanfattning : The thesis describes the neural precursor cell line RN33B transplanted subretinally to adult healthy and young dystrophic rat retina. The cell line is generated from E12,5 rat raphe nucleus and transduced with the temperature sensitive mutant of the Simian Virus 40 (SV40) large T-antigen. LÄS MER

  4. 13. Protein interactions involved in viral replication characterized by T7 phage display

    Författare :Hamid Houshmand; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; protein-protein interaktion; fagdisplayteknik; HCV; polyomavirus; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

    Sammanfattning : Protein interactions are essential for many cellular processes. By utilizing protein-protein interactions, viruses can infect their host cells and replicate. Phage display can be used for identification and characterization of protein-protein interactions. LÄS MER

  5. 14. Targeting RNA by the Antisense Approach and a Close Look at RNA Cleavage Reaction

    Författare :Jharna Barman; Lars Baltzer; Roger Strömberg; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; mRNA targeting; antisense oligonucleotides; target affinity; RNase H; Michaelis-Menten kinetics; exo-nuclease stability; NMR; pH titration; alkaline hydrolysis; Organisk kemi;

    Sammanfattning : This thesis summarizes the results of studies on two aspects of nucleic acids. Chemically modified antisense oligonucleotides (AONs) have been evaluated with regards to their suitability for mRNA targeting in an antisense approach (Paper I – III). LÄS MER

  7. 15. IGF-1R : studies on the expression and role in transformation

    Författare :Natalia Natalishvili; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Transformation is a complex nonlinear multistep process during which normal cell becomes cancerous. Main characteristics of transformed cells include uncontrolled growth, invasion and metastasis. LÄS MER