Sökning: "T-Lymphocytes"

Visar resultat 11 - 15 av 220 avhandlingar innehållade ordet T-Lymphocytes.

  1. 11. Studies of Rejection in Experimental Xenotransplantation

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Tomas Lorant; Uppsala universitet.; [2002]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Antibodies; cell culturing; cytokines; hyaluronan; immunosuppression; mouse; rat; rejection; T lymphocytes; xenotransplantation.; Kirurgi; MEDICINE Surgery; MEDICIN Kirurgi; Kirurgi; Surgery;

    Sammanfattning : One main hurdle to xenotransplantation, i.e. transplantation between different species, is the immunological barrier that the organ meets in the recipient. The aim of this thesis was to characterise xenogeneic rejection mechanisms by using the concordant mouse-to-rat heart transplantation model. LÄS MER

  2. 12. T cells in chronic obstructive pulmonary disease

    Detta är en avhandling från Umeå : Umeå university

    Författare :Ester Roos-Engstrand; Umeå universitet.; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; airway epithelium; bronchoscopy; bronchoalveolar lavage; endobronchial mucosal biopsies; inflammation; flow cytometry; T lymphocytes; CD25; CD127; FoxP3; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Lung diseases; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Lungsjukdomar; lungmedicin; Lung Medicine;

    Sammanfattning : Background: Tobacco smoking is the main cause of chronic obstructive pulmonary disease, COPD, but the mechanisms by which cigarette smoke induces COPD are still elusive. T lymphocytes have been implicated in the pathogenesis of the disease, but their role in the airway inflammation in COPD is not fully understood. LÄS MER

  3. 13. An experimental study on the interaction between the neuro-endocrine and immune systems in the gastrointestinal tract

    Detta är en avhandling från Umeå : Umeå universitet

    Författare :Bi-Feng Qian; Umeå universitet.; Umeå universitet.; [2001]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gastrointestinal tract; neuro-endocrine system; substance P; vasoactive intestinal polypeptide; vagus nerves; mucosal immune system; T lymphocytes; cytokines; inflammation; mouse;

    Sammanfattning : The mucosa lining of the gastrointestinal (GI) tract is in immediate contact with food nutrients to allow a rapid and efficient digestion and absorption and at the same time protects against the incessant risk of attack from pathogenic microbes. Maintenance of normal physiological activities in the GI tract is dependent on a number of regulatory interactions between the nervous, endocrine, and immune systems, as well as environmental and genetic factors. LÄS MER

  4. 14. Shb and Its Homologues: Signaling in T Lymphocytes and Fibroblasts

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Cecilia Lindholm; Uppsala universitet.; [2002]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Shb; T cell receptor; IL-2 receptor; PDGF receptor; cell signaling; adapter proteins; LAT; Vav; PLC-g1; SLP-76; JAK1; JAK3; Jurkat cells; T cells; NK cells; Apoptosis.; Cellbiologi; MEDICINE Morphology; cell biology; pathology Cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Sammanfattning : Stimulation of the T cell receptor (TCR) induces tyrosine phosphorylation of numerous intracellular proteins, leading to activation of the interleukin-2 (IL-2) gene in T lymphocytes. Shb is a ubiquitously expressed adapter protein, with the ability to associate with the T cell receptor and several signaling proteins in T cells, including: the TCR ζ-chain, LAT, PLC-γ1, Vav, SLP-76 and Gads. LÄS MER

  5. 15. Molecular and Cellular Complexity of Glioma Highlights on the Double-Edged-Sword of Infiltration Versus Proliferation and the Involvement of T Cells

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Demet Çağlayan; Uppsala universitet.; [2012]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glioma; Sox2; Sox21; Snail; Bone morphogenetic protein; Sleeping Beauty; Gliomatosis Cerebri; T lymphocytes; T regulatory lymphocytes; Oncology; Onkologi; Biology; Biologi;

    Sammanfattning : Glioblastoma multiforme (GBM), the most common and malignant brain tumor, is characterized by high molecular and cellular heterogeneity within and among tumors. Parameters such as invasive growth, infiltration of immune cells and endothelial proliferation contribute in a systemic manner to maintain the malignancy. LÄS MER