Sökning: "T regulatory cell"

Visar resultat 6 - 10 av 395 avhandlingar innehållade orden T regulatory cell.

  1. 6. Preparatory Studies to Introduce Regulatory T Cells in Clinical Transplantation

    Författare :David Berglund; Gunnar Tufveson; Olle Korsgren; David Sachs; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transplantation; Tolerance; Cell therapy; Regulatory T cell; In vivo imaging; Cell purification;

    Sammanfattning : Solid organ transplantation has evolved from being an experimental procedure to a life-saving treatment for patients with end-stage organ failure. The risk of losing a transplant due to acute rejection is very low with the use of modern immunosuppressive protocols and the short-term results are impressive. LÄS MER

  3. 7. Human intestinal T lymphocytes : a comparative analysis of phenotype and function in normal and inflamed mucosa

    Författare :Silvia Melgar; Nadine Cerf-Bensussan; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human intestinal mucosa; intraepithelial lymphocyte; lamina propria lymphocyte; γδ T cell; regulatory T cell; cytotoxicity; cytokine; basal lymphoid aggregate; ulcerative colitis; Crohn s disease;

    Sammanfattning : The epithelial lining of the gut must allow immediate contact with beneficial components as nutrients and normal microflora. At the same time it runs the constant risk of attack from pathogenic microbes and noxious agents. LÄS MER

  4. 8. Regulatory mechanisms controlling T cell activity

    Författare :Anette Sundstedt; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; T cell superantigen anergy interleukin-2 transcription factor cytotoxicity; serology; Immunology; Immunologi; serologi;

    Sammanfattning : This thesis is based on work studying the immunoregulatory mechanisms that govern the balance between activation and inactivation of T lymphocytes. Most of the work has been carried out in an experimental system using a T cell receptor (TCR-Vb3) transgenic mouse strain to obtain a homogenous T-cell population and utilizing the properties of bacterial superantigens to induce T cell responses and unresponsiveness in vivo. LÄS MER

  5. 9. Functional collaboration between HLH transcription factors in B cell development

    Författare :Ramiro Gisler; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; E47; Early B cell Factor EBF ; Clinical genetics; Klinisk genetik; HLH proteins; transcription factors; gene expression; B cell development; transcription regulation;

    Sammanfattning : The cells in B cell development can be divided into several subgroups or fractions, e.g. early-pro-B-, pro-B, large-pre-B-, small-pre-B-, immature and mature B cells, where the stages reflect the maturity degree of the cells. LÄS MER

  7. 10. Dynamic regulation of DNA methylation in human T-cell biology

    Författare :Antonio Lentini; Colm Nestor; Mikael Benson; Huan Zhang; Mika Gustafsson; Ian R. Adams; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : T helper cells play a central role in orchestrating immune responses in humans. Upon encountering a foreign antigen, T helper cells are activated followed by a differentiation process where the cells are specialised to help combating the infection. LÄS MER