Sökning: "T lymphocytes"

Visar resultat 16 - 20 av 459 avhandlingar innehållade orden T lymphocytes.

  1. 16. T-cell responses to Helicobacter pylori in humans and a possible role of regulatory T cells

    Författare :Anna Lundgren; Göteborgs universitet; []
    Nyckelord :Helicobacter pylori; mucosal immunology; stomach; duodenum; asymptomatic; duodenal ulcer; gastric adenocarcinoma; T cells; regulatory T cells; dendritic cells; T-cell recruitment;

    Sammanfattning : Helicobacter pylori colonize the stomach and areas of gastric metaplasia in the duodenum. The bacteria induce both local and systemic immune responses, but despite this, the infection normally persists for life and causes chronic gastritis in all infected subjects and peptic ulcers or gastric cancer in 10-20% of infected individuals. LÄS MER

  3. 17. Adoptive T Cell Therapy of Viral Infection and Cancer : Ex vivo Expansion of Cytomegalovirus- and Prostate Antigen-specific T Cells

    Författare :Björn Carlsson; Magnus Essand; Thomas Tötterman; Malcolm Brenner; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Immunotherapy; Adoptive T cell therapy; Dendritic cell; T cell; Tetramer; Cytomegalovirus; Transplantation; pp65; Prostate cancer; TARP; Prostate antigens; Immunologi; Immunology; Immunologi;

    Sammanfattning : The main focus of my thesis has been to develop protocols for generating antigen-specific cytotoxic T lymphocytes (CTLs) and T helper cells (TH) for adoptive transfer to treat cytomegalovirus (CMV) disease and prostate cancer. CMV viremia is a severe complication in immunocompromised stem cell transplanted patients. LÄS MER

  4. 18. T cells in chronic obstructive pulmonary disease

    Författare :Ester Roos-Engstrand; Anders Blomberg; Anders Bucht; Annelie F Behndig; Magnus Sköld; Claes-Göran Löfdahl; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; airway epithelium; bronchoscopy; bronchoalveolar lavage; endobronchial mucosal biopsies; inflammation; flow cytometry; T lymphocytes; CD25; CD127; FoxP3; Lung diseases; Lungsjukdomar; lungmedicin; Lung Medicine;

    Sammanfattning : Background: Tobacco smoking is the main cause of chronic obstructive pulmonary disease, COPD, but the mechanisms by which cigarette smoke induces COPD are still elusive. T lymphocytes have been implicated in the pathogenesis of the disease, but their role in the airway inflammation in COPD is not fully understood. LÄS MER

  5. 19. Transcriptional control of CD4+ T lymphocytes

    Författare :Peter C J Janson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The immune system can respond to various types of pathogens such as bacteria, viruses, tumors and parasites. The ability to provide protection against different types of pathogens partly relies on development of alternative T effector cells with separate effector functions. LÄS MER

  7. 20. Extrathymic T cell receptor gene rearrangement in human alimentary tract

    Författare :Anna Bas; Marie-Louise Hammarström; Sten Hammarström; Adrian Hayday; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; T cell maturation; recombination activating gene; preTα; human intestinal mucosa; intraepithelial lymphocytes; lamina propria lymphocytes; nasopharyngeal tonsil; Immunologi; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : T lymphocytes regulate the initiation, duration, and magnitude of adaptive immune responses and function as effector cells in cell mediated immunity. To become immunologically competent they must generate functional antigen receptors. This process takes place in the thymus and requires somatic recombination of T cell receptor (TCR) genes. LÄS MER