Sökning: "T Brown"

Visar resultat 21 - 25 av 25 avhandlingar innehållade orden T Brown.

  1. 21. FOXC2 : a regulator of adipocyte metabolism

    Författare :Anna Cederberg; Göteborgs universitet; []
    Nyckelord :FOXC2; forkhead; winged helix; obesity; diabetes; adipocyte; insulin resistance;

    Sammanfattning : Obesity, hyperlipidemia and insulin resistance are common forerunners of type 2 diabetes, a serious and increasingly prevalent disease in both the industrialised part of the world as well as in third world countries. We have identified the human transcription factor gene FOXC2 as a key regulator of adipocyte metabolism. LÄS MER

  3. 22. Studies of the C/EBP family of transcription factors : cloning, regulation, and expression

    Författare :Per Antonson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Basic leucine zipper; CCAATEnhancer Binding Protein; CEBP; DNA binding protein; Gene expression; Transcription factor;

    Sammanfattning : The CCAAT/Enhancer Binding Protein (C/EBP) family belongs to the basic leucine zipper class of transcription factors with a total of 6 members having been identified in this family so far. This gene family has been mainly implicated in regulation of cell specific gene expression and differentiation. LÄS MER

  4. 23. Ligand-receptor interactions and signaling cross-talk in the TGF-b superfamily

    Författare :Andries Blokzijl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The transforming growth factor-beta (TGF-beta) superfamily of secreted polypeptide growth factors forms part of an evolutionary conserved signaling pathway, present in diverse organisms from flies to humans, used in intercellular communication. The TGF-beta family comprises more than 40 members in vertebrates, Caenorhabditis elegans and Drosophila melanogaster. LÄS MER

  5. 24. Challenging the mystique Connection. Deciphering cell-matrix interactions role in atherosclerosis and restenosis

    Författare :Vignesh Murugesan; Kärlväggsbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dystrophin glycoprotein complex; beta-sarcoglycan; dystrophin; Plaque; vascular smooth muscle cells; atherosclerosis; restenosis;

    Sammanfattning : Atherosclerosis is the underlying cause for myocardal infarction, stroke and peripheral arterial disease, collectively referred to as cardiovascular diseases. These represent the major cause of death globally. LÄS MER

  7. 25. Effects of nitrogen deposition on the growth, metabolism and activity of ectomycorrhizal fungi

    Författare :Magnus Ellström; MEMEG; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Nitrogen deposition; Ectomycorrhizal fungi; Symbiosis; SOM modification; Carbon starvation; Metabolism; Nitrogen leakage; IR-spectroscopy; Mesh bags; Microarray; Axenic growth; Transcriptomics.;

    Sammanfattning : Elevated nitrogen (N) deposition is an environmental problem that can affect plants and microorganisms, which are vital for the terrestrial N and carbon (C) cycles. This thesis has investigated the response of ectomycorrhizal fungi (EMF) to increased N deposition. LÄS MER