Sökning: "Systemic lupus erythematosus SLE"

Visar resultat 16 - 20 av 130 avhandlingar innehållade orden Systemic lupus erythematosus SLE.

  1. 16. Systemic lupus erythematosus : biomarkers and biologics

    Författare :Ioannis Parodis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Systemic lupus erythematosus (SLE) is a chronic autoimmune disease, predominantly affecting women of childbearing age. The pathogenesis of SLE is multifactorial, and the clinical phenotype and course vary considerably within the SLE population. Multiple organs can be involved, lupus nephritis (LN) being one of the most severe manifestations. LÄS MER

  3. 17. Functional Role of Genetic Polymorphisms Associated with Systemic Lupus Erythematosus

    Författare :Sara E Löfgren; Ulf Gyllensten; Jan Hillert; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; autoimmunity; systemic lupus erythematosus; genetic association; single nucleotide polymorphism; IRF5; CD226; miR-146a; Medical Science; Medicinsk vetenskap; Medical Genetics; Medicinsk genetik;

    Sammanfattning : Systemic lupus erythematosus (SLE) is a chronic and complex autoimmune disorder characterized by a failure in the mechanism of self-tolerance and production of autoantibodies, potentially affecting any organ in the body. The genetic factors behind the disease have been extensively studied in the past years and to date a list of more than 30 loci have been associated with SLE. LÄS MER

  4. 18. B cell depleting therapy in systemic lupus erythematosus

    Författare :Thórunn Jónsdóttir; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Systemic Lupus Erythematosus; Lupus nephritis; B cells; rituximab;

    Sammanfattning : Systemic Lupus Erythematosus (SLE) is a chronic autoimmune inflammatory disease characterized by multiple organ involvement, production of a wide range of autoantibodies and local formation or tissue deposition of immune complexes in the affected organs. Lupus nephritis (LN) is a common and serious organ involvement in patients with SLE. LÄS MER

  5. 19. Studies on Neuropsychiatric Manifestations and Genetic Factors in Systemic Lupus Erythematosus

    Författare :Andreas Jönsen; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skeleton; Genetics; Systemic Lupus Erythematosus; Neuropsychiatric; rheumatology locomotion; Skelett; muskelsystem; reumatologi; muscle system;

    Sammanfattning : Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disease encompassing a wide range of symptoms that can emanate from pathology in virtually any organ system. Severe SLE includes involvement of the central nervous system and kidneys. LÄS MER

  7. 20. Studies on Cardiovascular Disease in Systemic Lupus Erythematosus

    Författare :Helena Tydén; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :SLE glomerulonephritis; endothelial activation; type I interferon; S100 Proteins; Cardiovascular Disease;

    Sammanfattning : .... LÄS MER