Sökning: "Synteny"
Visar resultat 1 - 5 av 21 avhandlingar innehållade ordet Synteny.
1. Evolution of acetylcholine receptors and study of the anatomy of the mouse brain reward system
Sammanfattning : This thesis work is divided in two parts. In the first part, I make use of the transgenic TRPV1-Cre mouse line as a tool to investigate the midbrain ventral tegmental area (VTA). LÄS MER
2. Quantitative Genetics and Genome Structure in a Wild Population: the Use of a Great Reed Warbler Pedigree
Sammanfattning : Long-term studies of birds play an important role in the understanding of quantitative traits in natural populations. The relative ease by which individual birds can be monitored and caught in the wild enable us collect detailed information from individuals throughout their life time, sometimes from several generations in a population. LÄS MER
3. Evolutionary Analysis of the Insulin-Relaxin Gene Family from the Perspective of Gene and Genome Duplication Events
Sammanfattning : Paralogs arise by duplications and belong to families. Ten paralogs (insulin; IGF-1 and -2; INSL3-6 and 3-relaxins) constitute the human insulin-relaxin family. The aim of this study was to outline the duplications that gave rise to the vertebrate insulin-relaxin genes and the chromosomal regions in which they reside. LÄS MER
4. Evolution and Pharmacology of Receptors for Bradykinin and Neuropeptide Y in Vertebrates
Sammanfattning : The bradykinin and neuropeptide Y (NPY) receptors belong to the superfamily of G-protein coupled receptors (GPCRs). The GPCRs form the largest class of therapeutic targets and it is therefore of great interest to investigate the pharmacological properties, functions and evolution of these receptors. LÄS MER
5. Probabilistic Modelling of Domain and Gene Evolution
Sammanfattning : Phylogenetic inference relies heavily on statistical models that have been extended and refined over the past years into complex hierarchical models to capture the intricacies of evolutionary processes. The wealth of information in the form of fully sequenced genomes has led to the development of methods that are used to reconstruct the gene and species evolutionary histories in greater and more accurate detail. LÄS MER