Sökning: "Syngeneic"

Visar resultat 1 - 5 av 60 avhandlingar innehållade ordet Syngeneic.

  1. 1. Transplantation of normal and decellularized syngeneic, allogeneic and xenogeneic cardiac tissue in mice and non-human primates

    Författare :Ketaki Methe; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Decellularization; Cardiac tissue; Syngeneic; Allogeneic; Xenogeneic; Non-human primate;

    Sammanfattning : Introduction Because of the restricted inherent capacity of regeneration and healing, transplantation is the only treatment for end-stage heart failure but it has limitations of donor shortage and graft rejection. Cardiac tissue engineering strategies might help to alleviate this problem. LÄS MER

  2. 2. Immunological and Inflammtory Responses against Intrastriatal Neural Grafts in the Rat

    Författare :Wei-Ming Duan; Neurobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurology; MHC; Rat; Brain; Xenogeneic; Allogeneic; Syngeneic; Cytokine; Inflammation; Neural transplantation; Immunology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Sammanfattning : Intracerebral neural transplantation offers a new strategy to combat Parkinson’s and Huntington’s diseases. However, a host immune response against a histoincompatible neural graft in the brain may jeopardize transplant survival. LÄS MER

  3. 3. Inflammation in Parkinson’s Disease and Experimental Neural Transplantation. Role of Cellular Responses, Cytokines and Immunosuppression in Graft Rejection

    Författare :Bilal Mirza; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; graft rejection.; pig; human; rat; xenogeneic; allogeneic; syngeneic; transplantation immunology; immunosuppression; cytokines; neural transplantation; Parkinson’s Disease; inflammation; neurodegeneration; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Sammanfattning : Abstract: Parkinson’s disease (PD) is a common neurodegenerative disorder. There is no proven protection, but many treatments can partially improve symptoms. The disease is caused by monogenetic mechanisms in very few cases, but for the majority of patients the etiology is unknown. LÄS MER

  4. 4. High-Dose Radioimmunotherapy and Extracorporeal Depletion in A Syngeneic Rat Tumor Model

    Författare :Linda Mårtensson; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : ABSTRACT Radioimmunotherapy (RIT) consists of using monoclonal antibodies (mAbs) recognizing tumor-selective antigens, as carriers of cytotoxic radionuclides to tumor tissue. RIT has been effective in lymphoma but less successful in solid tumors. LÄS MER

  5. 5. Prevention of type 1 diabetes mellitus in experimental studies

    Författare :Maria Holstad; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Cytokines; inducible nitric oxide synthase; nitric oxide; NOD mice; pancreatic islets; prolactin; syngeneic islet transplantation; tumour necrosis factor alpha; type 1 diabetes mellitus; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Sammanfattning : The aim of the study was to examine the immune response and different immunoprotective strategies in experimental type 1 diabetes mellitus. The autoimmune destruction of the insulin-producing pancreatic β-cells that leads to type 1 diabetes is complex and incompletely understood. LÄS MER