Sökning: "Sylvia Packham"
Hittade 1 avhandling innehållade orden Sylvia Packham.
1. From membrane to nucleus : new roles and functions of SUMOylated IGF-1R and EGFR
Sammanfattning : Cell surface receptor tyrosine kinases (RTKs) role in cell signaling have been studied for decades and their role in cancer progression are undisputable. The insulin-like growth factor 1 receptor, IGF-1R, has been demonstrated to play a critical part in tumorigenesis; downregulation of the IGF-1R in tumor xenografts results in complete tumor regression. LÄS MER
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