Sökning: "Sven Engström"
Visar resultat 1 - 5 av 8 avhandlingar innehållade orden Sven Engström.
1. Quality, costs and the role of primary health care
Sammanfattning : The general aim of this thesis is to describe and analyse the role of primary care in health care systems in terms of health, health care utilisation and costs, and to study the feasibility of retrieval of data from computerised medical records to monitor medical quality.The thesis includes five studies, a systematic literature review, a register study of utilisation of hospital and primary care, a study based on data from computerised medical records of individual patients cost for primary care, and two studies of management of respiratory infections in primary care based on data from computerised medical records of twelve health centres. LÄS MER
2. Chemical genetics discloses the importance of heme and glucose metabolism in Chlamydia trachomatis pathogenesis
Sammanfattning : Chlamydiae are important human bacterial pathogens with an intracellular life cycle that consists of two distinct bacterial forms, an infectious form (EB) that infects the eukaryotic host cell, and a non-infectious form (RB) that allows intracellular proliferation. To be successful, chlamydiae need to alternate between EB and RB to generate infectious EB’s which are competent to infect new host cells. LÄS MER
3. Drug Partitioning into Natural and Artificial Membranes : Data Applicable in Predictions of Drug Absorption
Sammanfattning : When drug molecules are passively absorbed through the cell membrane in the small intestine, the first key step is partitioning of the drug into the membrane. Partition data can therefore be used to predict drug absorption. LÄS MER
4. Bilayer Discs - Fundamental Investigations and Applications of Nanosized Membrane Models
Sammanfattning : The bilayer disc is a flat, lipid aggregate structure in the nanometre regime. It is composed of a bilayer of amphiphilic molecules with micelle-forming amphiphilic molecules supporting the rim, which prevent disc fusion and self-closure. LÄS MER
5. Phase Transformations in Solid Pharmaceutical Materials Studied by AFM, ESCA, DSC and SAXS
Sammanfattning : Mixing excipients is a common way to produce pharmaceutical materials with suitable properties for drug formulation. An understanding of the basic mechanisms involved in the formation and transformation of the structures of solid state mixtures is crucial if one is to be able to produce materials with the desired properties in a reliable way. LÄS MER
