Sökning: "Susanna 2002"

Visar resultat 1 - 5 av 8 avhandlingar innehållade orden Susanna 2002.

  1. 1. Structure-function studies of GDNF and other members of the TGF-beta superfamily

    Författare :Susanna Eketjäll; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The glial cell line-derived neurotrophic factor (GDNF) family is a distant subclass of the TGF-beta superfamily. The GDNF family of ligands, consisting of GDNF, neurturin (NTN), artemin (ART) and persephin (PSP), are potent survival and differentiation factors for neurons in the central and peripheral nervous systems. LÄS MER

  3. 2. T cell Tolerance - Cellular and molecular features of immune regulation

    Författare :Susanna Grundström; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Immunologi; serologi; serology; Immunology; JAK STAT.; NFkB; suppression; IL-2; superantigen; T cells; tolerance;

    Sammanfattning : The immune system has evolved regulatory mechanisms in order to balance the effects of deleterious immune responses. Such immunological tolerance may be specifically acquired by lymphocytes, although different cells of the immune system participate in the induction and maintenance of tolerance. LÄS MER

  4. 3. On age related changes in axons and glia of the central nervous system

    Författare :Susanna Kullberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Aging; synaptic input; spinal cord; hippocampus; amino acid neurotransmitters; astrocyte; microglia; oligodendroglia; C bouton; cholinergic; monoaminergic; cytokine;

    Sammanfattning : A growing body of evidence shows that phenotypic changes including axon aberrations, rather than loss of neurons, account for behavioral impairments during aging. The present thesis was undertaken to investigate the occurrence of axon aberrations in relation to transmitter identity, glial reaction and sensorimotor disturbances. LÄS MER

  5. 4. Megencephaly, significance, biology and identification of a genetic cause

    Författare :Susanna Petersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Megalencephaly; brain; mceph; ion-channel; DNA; mutation; truncation; frameshift; seizure; plasticity; neurotrophin; growth factor; neuropeptide; positional cloning;

    Sammanfattning : Enlarged brain is termed megencephaly or megalencephaly, and is defined as a brain volume above the 98th percentile. It is a major sign in several neurological diseases with symptoms ranging from very mild to lethal, including mental retardation, low intelligence, motoric and neurological disturbances, seizures and dysmorphic features. LÄS MER

  7. 5. Public Perceptions of Gene Technology : On the edge of risk society

    Författare :Susanna Öhman; Mittuniversitetet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Sociology; Sociologi;

    Sammanfattning : .... LÄS MER