Sökning: "Surrogate models"

Visar resultat 1 - 5 av 62 avhandlingar innehållade orden Surrogate models.

  1. 1. Reliability-Based Assessment and Optimization of High-Speed Railway Bridges

    Författare :Reza Allahvirdizadeh; Raid Karoumi; Andréas Andersson; Daniel Straub; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; High-speed railway bridges; Bridge dynamics; Running safety; Passenger comfort; Structural reliability; Meta-models; Surrogate models; Adaptive sampling; Reliability-based design optimization; Höghastighetsjärnvägsbroar; Brodynamik; Trafiksäkerhet; Passagerarkomfort; Konstruktioners tillförlitlighet; Metamodeller; Surrogatmodeller; Adaptiv sampling; Tillförlitlighetsbaserad designoptimering; Structural Engineering and Bridges; Bro- och stålbyggnad;

    Sammanfattning : Increasing the operational speed of trains has attracted a lot of interest in the last decades and has brought new challenges, especially in terms of infrastructure design methodology, as it may induce excessive vibrations. Such demands can damage bridges, which in turn increases maintenance costs, endangers the safety of passing trains and disrupts passenger comfort. LÄS MER

  3. 2. Optimization of Castings by using Surrogate Models

    Författare :Erik Gustafsson; Niclas Strömberg; Bo Torstenfelt; Linköpings universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Response Surface Methodology RSM ; Residual Stresses; Castings; Engineering mechanics; Teknisk mekanik;

    Sammanfattning : In this thesis structural optimization of castings and thermomechanical analysis of castings are studied.In paper I an optimization algorithm is created by using Matlab. The algorithm is linked to the commercial FE solver Abaqus by using Python script. LÄS MER

  4. 3. Challenge models and biomarkers of human intestinal barrier function

    Författare :María Fernanda Roca Rubio; Julia König; Robert J Brummer; Richard Forsgård; Kaatje Lenaerts; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bacterial translocation; biomarkers; challenge models; intestinal barrier function; intestinal permeability; irritable bowel syndrome; physiological stress; psychological stress;

    Sammanfattning : The intestinal barrier is an essential component in maintaining human health, and several diseases and disorders have been associated with a disrupted intestinal barrier function. To evaluate the efficacy of different interventions intended to strengthen intestinal barrier function, there is a need for both appropriate challenge models as well as easily accessible biomarkers. LÄS MER

  5. 4. Sampling from molecular unnormalized distributions with Deep Generative Models

    Författare :Juan Viguera Diez; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; machine learning; Cheminformatics; conformational sampling; generative models; drug discovery; Boltzmann generators;

    Sammanfattning : This thesis investigates how Deep Generative Models (DGMs) can address important drug discovery problems involving sampling from unnormalized distributions. It consists of two papers focusing on this challenge’s aspects: molecular design and conformational sampling. LÄS MER

  7. 5. Improving the Dynamic Design Philosophy of High-Speed Railway Bridges Using Reliability-Based Methods

    Författare :Reza Allahvirdizadeh; Raid Karoumi; Andreas Andersson; Christoph Adam; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; High-speed railway bridges; Bridge dynamics; Running safety; Passenger comfort; Structural reliability; Surrogate models; Active learning; Reliability-based design optimization; Partial safety calibration; Epistemic uncertainties; Höghastighetsjärnvägsbroar; Brodynamik; Trafiksäkerhet; Passagerarkomfort; Konstruktioners tillförlitlighet; Surrogatmodeller; Aktivt lärande; Tillförlitlighetsbaserad optimering; Kalibrering av partialkoefficienter; Epistemiska osäkerheter; Bro- och stålbyggnad; Structural Engineering and Bridges;

    Sammanfattning : Modern railway infrastructures, especially bridges, are exposed to significant vibrations with potential safety implications. In this context, previous studies have shown the inconsistency and inadequacy of some conventional design methods necessitaing them to be improved. The assessment of safety inherently deals with uncertainties. LÄS MER