Sökning: "Surgery transplantation orthopaedics traumatology Kirurgi ortopedi traumatologi serologi Immunologi"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden Surgery transplantation orthopaedics traumatology Kirurgi ortopedi traumatologi serologi Immunologi.

  1. 1. Tissue Factor in Transplantation -aspects on expression and inhibition

    Författare :Cecilia Österholm; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nephrotoxicity; tissue factor; transplantation; ischemia-reperfusion injury; serologi; Immunologi; serology; Immunology; extracellulära vätskor; Hematologi; extracellular fluids; traumatology; Kirurgi; Urology; nephrology; Urologi; nefrologi; Surgery; orthopaedics; ortopedi; traumatologi; Haematology; chronic rejection;

    Sammanfattning : Organ transplantation provides a treatment of end-stage disease primarily in the kidney, liver and heart. The immunosuppressive treatment regimens of today efficiently prevent early acute rejection; however the long-term survival has not improved to the same extent. LÄS MER

  3. 2. The morselized and impacted bone graft. Animal experiments on proteins, impaction and load

    Författare :Magnus Tägil; Lund Ortopedi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; traumatology; orthopaedics; Surgery; load; growth factors; graft healing; remodeling; allograft; Impaction grafting; morselized graft; Kirurgi; ortopedi; traumatologi; Immunology; serology; transplantation; Immunologi; serologi;

    Sammanfattning : This thesis focuses on the healing and remodeling of the morselized and impacted bone allograft, commonly used in revision of loosened hip prostheses with osteolysis. The influence on remodeling by the impaction procedure per se was analyzed, as well as the effects of endogenous bone graft proteins, and an exogenously applied growth factor (OP-1). LÄS MER

  4. 3. Effects of ionising and non-ionising radiation in cell systems and a rat model for immuno-therapy

    Författare :Catrin Baureus Koch; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kirurgi; ortopedi; traumatologi; Neurology; traumatology; transplantation; Surgery; orthopaedics; cell cultures; abscopal effect; serologi; Immunologi; serology; Immunology; rat tumour model; radiation therapy; radiation sterilisation; pulsed electric fields; interferon-gamma; immuno-gene therapy; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; glioblastoma multiforme;

    Sammanfattning : The most malignant brain tumour, glioblastoma multiforme (GBM), has an utterly bad prognosis. In spite of all available therapy, the mean survival time is less than a year. In the unique BRIGTT project (Brain Immuno Gene Tumour Therapy), patients at the Dept of Neurosurgery. LÄS MER

  5. 4. Costimulation Blockade in Experimental Transplantation

    Författare :Helene Malm; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi; serologi; Immunologi; serology; Immunology; Medicin människa och djur ; Medicine human and vertebrates ; graft survival; anti-CD40L; CTLA4Ig; anti-LFA-1; costimulation blockade;

    Sammanfattning : Transplantation is the only cure for end-stage organ failure. With the transplantation follows the need for continuous treatment with immunosuppressive agents for as long as the graft functions, which entails major side effects. Less toxic treatments are therefore in great demand. Preferably, the treatment should also be limited in time. LÄS MER

  7. 5. Inhibition of acute allogaft rejection - experimental transplant studies with biological and chemical immunosuppressants

    Författare :Zhongquan Qi; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; Immunology; tacrolimus; MNA; leflunomide; cyclosporine; drug effects; graft survival; immunosuppression; heart; animal; transplantation; Immunologi; serologi; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

    Sammanfattning : In clinical transplantation immunosuppressive agents are used in combination with the objective to achieve additive effects and less toxicity. A large number of novel drugs are candidates for clinical introduction at this time and experiments in animal models have an important role to play. LÄS MER