Sökning: "Sulfolobus"

Visar resultat 11 - 15 av 15 avhandlingar innehållade ordet Sulfolobus.

  1. 11. Microbial adaptations and controlling mechanisms of surface-associated microhabitat heterogeneity in aquatic systems

    Författare :Jan Torsten Jeske; Stefan Bertilsson; Annelie Wendeberg; Andreas Schramm; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; microbial habitat heterogeneity; Biology with specialization in Limnology; Biologi med inriktning mot limnologi;

    Sammanfattning : Habitat heterogeneity is a driving factor for speciation and ecosystem functioning and is well studied in macro-ecology. Yet our understanding of microbial adaptations, and governing processes is incomplete. LÄS MER

  3. 12. Thermodynamics of protein-DNA interactions

    Författare :Thomas Lundbäck; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :DNA-protein interactions; molecular recognition; thermodynamics; specificity.dehydration; salt dependence.;

    Sammanfattning : This thesis treats the molecular recognition between DNA-binding proteins and DNA and the way these interactions are affected by the surrounding water solution and dissolved solutes. The work involves studies on the thermodynamics of sequence specific DNA-binding of the human glucocorticoid receptor DNA-binding domain and the nonsequence specific DNA- binding of Sso7d from the archaeon Sulfolobus solfataricus. LÄS MER

  4. 13. Shining light on unknown function proteins

    Författare :Riccardo Diamanti; Martin Högbom; Hans-Petter Hersleth; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; proteins; membrane proteins; metalloproteins; biochemistry; metabolism; biokemi; Biochemistry;

    Sammanfattning : The study of protein structure and function is a fundamental step for understanding biological systems and for creating a solid ground for future drug development. Despite the development of novel ground-breaking biochemical and bioinformatical tools in the last decades, most proteins found in nature still have unknown assigned function. LÄS MER

  5. 14. Beta-Glycosidases from Hyperthermophiles as Biocatalysts

    Författare :Therese Hansson; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Bioteknik; Biochemical technology; Biokemisk teknik; Proteins; enzymology; Proteiner; enzymologi; Biotechnology; high temperatures; water activity; activity; selectivity; hexanol; hexyl-b-glycoside; galacto-oligosaccharides; lactose; hyperthermostable b-glycosidase; hydrolysis; optimisation; transglycosylation;

    Sammanfattning : The thesis concerns glycosyl transfer with use of b-glycosidases, most of them from hyperthermophilic organisms. Both optimisation of the reaction conditions and protein engineering in terms of site-directed mutagenesis were used to improve b-glycosidase-catalysed reactions. LÄS MER

  7. 15. Functional genomics at the interface of protein expression and biophysical analysis

    Författare :Xiaoqiu Wu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Protein characterization is central to any functional genomics effort, hence protein expression and purification play fundamental roles in these initiatives. In this study strategies for protein expression in E. coli were analysed, and several parameters were investigated respect to high-level expression of functional proteins. LÄS MER