Sökning: "Substance Use Disorders"

Visar resultat 21 - 25 av 66 avhandlingar innehållade orden Substance Use Disorders.

  1. 21. Gene Therapy for Neurological Disorders

    Författare :Jan Tönnesen; Lund Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; epileptiform activity; striatum; organotypic culture; electrophysiology; Wnt5a; synaptic connectivity.; cell transplantation; hippocampus; neural stem cells; epilepsy; functional integration; Parkinson’s disease; optogenetics; Gene therapy;

    Sammanfattning : Gene therapy is an attractive strategy for neurological disorders, such as Parkinson’s disease and epilepsy, for several reasons. Introduction of genes with a therapeutic potential can be achieved locally, by accurate injections in the compromised tissue, and release of a transgene therapeutic substance can be regulated by the surrounding host neural circuitry. LÄS MER

  3. 22. Cannabis use : understanding other illicit drug use, drug-related morbidity and dependence

    Författare :Rynaz Rabiee; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Amid increased prevalence globally of both cannabis use, and cannabis use disorder (CUD), changes of the legal status of use, as well as increased cannabis potency, it is important to increase the understanding about the health effects from using this psychoactive substance. Improved understanding will provide better prerequisites when shaping policies and healthcare systems targeting affected individuals. LÄS MER

  4. 23. Personality traits among individuals who as adolescents consulted for a substance use problem

    Författare :Malin Hemphälä; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Adolescent antisocial behavior including substance misuse is associated with negative consequences both for the individual and the society, for example school drop-out, and high costs in the criminal justice and health systems. Further understanding of adolescent substance misuse is needed to inform treatment programs. LÄS MER

  5. 24. Offenders with mental health problems and problematic substance use : treatment interventions and crime relapse

    Författare :Natalie Durbeej; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: The relationships between problematic substance use, mental health problems and criminal behavior have been firmly established in research. Offenders with mental health problems and concurrent problematic substance use have high risk of reoffending and may display low rates of treatment retention. LÄS MER

  7. 25. Postmenopausal disorders with special reference to urinary incontinence : An epidemiological, experimental and clinical study

    Författare :Åsa Stenberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics and gynaecology; Obstetrik och kvinnosjukdomar; Obstetrics and women s diseases; Obstetrik och kvinnosjukdomar; Medicine; medicin;

    Sammanfattning : A cross-sectional study of the whole female population of ages 61, 71 and 81 years in a defined part of Sweden was undertaken to investigate the prevalence and severity of postmenopausal symptoms, especially lower genital tract disorders, and to relate their symptoms to reported oestrogen replacement therapy (ERT) (studies I and II). A new substance for endoscopic treatment of urinary incontinence, dextranomers in hyaluronan, (DiHA), was monitored experimentally in terms of tissue reaction, volume changes, DNA changes (study III), and possible migration of particles to distant organs (study IV). LÄS MER