Sökning: "Subnuclear localization"

Hittade 3 avhandlingar innehållade orden Subnuclear localization.

  1. 1. Chromatin Dynamics in the Fission Yeast, Schizosaccharomyces pombe

    Författare :Carolina Kristell; Pernilla Bjerling; Per Sunnerhagen; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chromatin; Gene induction; Silencing; Subnuclear localization; Stress; Molecular biology; Molekylärbiologi; Molekylär genetik; Molecular Genetics;

    Sammanfattning : In the eukaryotic cell nucleus, spatial organization and dynamics of the genome is important in the regulation of gene expression. This thesis describes the use of the fission yeast, Schizosaccharomyces pombe, to study chromatin regulation and dynamics. We used nitrogen starvation to induce transcription of genes in fission yeast cells. LÄS MER

  3. 2. The Adenovirus L4-33K Protein : A Key Regulator of Virus-specific Alternative Splicing

    Författare :Heidi Törmänen Persson; Göran Akusjärvi; Stefan Schwartz; Marie Öhman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; L4-33K; adenovirus; splicing; phosphorylation; localization; replication centers; L4-22K; MLTU; DNA-PK; DNA-dependent protein kinase; PKA; cAMP-dependent protein kinase; transcription sites; SR protein; Medical Virology; Medicinsk virologi;

    Sammanfattning : Adenoviruses have been extensively studied in the field of gene regulation, since their genes are subjected to a tightly controlled temporal expression during the virus lifetime. The early-to-late shift in adenoviral gene expression distinguishes two completely different programs in gene expression. LÄS MER

  4. 3. Identification and functional characterization of novel thioredoxin systems

    Författare :Anastasios E Damdimopoulos; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Antioxidants; Reactive Oxygen Species; Tbioredoxin; Tbioredoxin Reductase;

    Sammanfattning : Thioredoxins (Trx) are a class of small multifunctional 12-kDa proteins that are characterized by the redox active site Trp-Cys-Gly-Pro-Cys (WCGPC). In the oxidized (inactive) form of Trx (Trx-S2), the two cysteines at the active site form a disulfide bond. LÄS MER