Sökning: "Subfertility"

Visar resultat 1 - 5 av 15 avhandlingar innehållade ordet Subfertility.

  1. 1. Male Subfertility and Prostate Cancer Risk: Epidemiological and Genetic Studies

    Författare :Yasir Ruhayel; Malmö Molekylärgenetisk reproduktionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cytoplasmic and nuclear; Receptors; Prostatic neoplasms; genetic; Polymorphism; male; Infertility; Hypogonadism; Genetic association studies; Case–control studies; Androgens;

    Sammanfattning : Androgen action plays a pivotal role in male reproductive tract physiology and pathology. The androgen receptor (AR) gene harbors two codon repeat tracts: the CAG and GGN repeats, encoding corresponding amino acid sequences of variable length; the polyglutamine and polyglycine stretches, respectively. LÄS MER

  3. 2. New evidence on germ-cell testicular cancer aetiology

    Författare :Lorenzo Richiardi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Testicular neoplasm; Seminomas; Nonseminomas; Case-control study; Risk factors; Perinatal characteristics; Body size; Subfertility; Occurrence.;

    Sammanfattning : Testicular cancer has been increasing in incidence for at least 50 years in many populations, but its etiology remains elusive. We investigated several prenatal and postnatal factors in association with germ-cell testicular cancer risk. Moreover, we evaluated recent trends in testicular cancer incidence in Northern European countries. LÄS MER

  4. 3. Etiological insights into the testicular cancer epidemic

    Författare :Olof Akre; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Testicular neoplasms; seminoma; nonseminoma; epidemiology; etiology; risk factors; prenatal; fertility; birth weight; placenta; neonatal jaundice; cryptorchidism; hypospadias; preterm birth; Epstein-Barr virus; cytomegalovirus; Body Mass Index; height;

    Sammanfattning : The aim of this thesis was to search for causes of the testicular cancer epidemic through epidemiologic studies of testicular cancer and possibly related conditions, such as urogenital birth defects and subfertility. First, we assessed changes in fertility over time by studying time-to-pregnancy among primiparous women in Sweden from 1983 through 1993 using data from the Medical Birth Registry. LÄS MER

  5. 4. Mental health in women with polycystic ovary syndrome

    Författare :Mattias Månsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Polycystic Ovary Syndrome (PCOS) is the most common hyperandrogenic condition in women. It is associated with several adverse health outcomes as subfertility, obesity, the metabolic syndrome, and skin issues. PCOS can be viewed as a naturally occurring model of the activating effect of androgens on women. LÄS MER

  7. 5. Aspects of the regulation of human sperm motility

    Författare :Pär K G Leijonhufvud; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In this thesis I address some of the possible causes for oligozoospermia and low sperm motility, two factors that, singly or in combination, are often seen in cases of male subfertility. In the first study we evaluated the effect on human spermatozoa of the toxicity of compounds present in diesel exhaust. LÄS MER