Sökning: "Studie om stress cancer"
Visar resultat 1 - 5 av 11 avhandlingar innehållade orden Studie om stress cancer.
1. Balancing - Cancer from a primary care perspective. Diagnosis, posttraumatic stress, and end-of-life care
Sammanfattning : This thesis explores cancer from a primary care perspective covering three areas: diagnosis, posttraumatic stress disorder (PTSD), and end-of-life care. We analyzed patient records of every child diagnosed with a malignancy in a defined area. During 12 years 68 children were diagnosed (incidence 14/100,000). LÄS MER
2. Development of Computational Methods for Cancer Research: Strategies for closing the feedback loop in omics workflows
Sammanfattning : As the ultimate workhorses of the living things, proteins undergo significant regulatory activity throughout the lifetime of a cell or an organism. Many complex diseases effect the protein composition, expression or modification in the cells or tissues they arise in. LÄS MER
3. Endothelial and cardiac effects of 5-fluorouracil. An experimental and clinical study
Sammanfattning : The cytostatic drug 5-fluorouracil (5-FU) has been shown to affect both morphology and function of vascular endothelium. These effects could be part of the pathophysiology for 5-FU induced cardiotoxicity. The present thesis explores the mechanisms of this endothelial toxicity. LÄS MER
4. Regulation and functions of basic helix-loop-helix transcription factors in neuroblastoma cells
Sammanfattning : Neuroblastoma is a childhood tumor derived from primordial neural crest cells. The tumor cells exhibit a phenotype similar to that of developing neuroblasts, which indicates that the tumor arises due to perturbed differentiation of the sympathetic nervous system. LÄS MER
5. A high-throughput pathology approach for further insight into the role of RBM3 as a biomarker of prognosis and chemotherapy response in human cancer
Sammanfattning : Cancer incidence is increasing and it is the number one cause of death worldwide. Cancer is a highly heterogeneous disease and there is a great need for new early diagnostic, prognostic and treatment predictive biomarkers in order to improve patient outcomes. LÄS MER