Sökning: "Structural"

Visar resultat 6 - 10 av 5821 avhandlingar innehållade ordet Structural.

  1. 6. Structural and Functional Studies of Gelsolin Family Proteins

    Författare :Qing Ma; Robert Robinson; Roger Karlsson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Structural biology; Strukturbiologi;

    Sammanfattning : The actin cytoskeleton is a complex structure that performs a wide range of cellular functions including: cell locomotion, cytokinesis, chemotaxis, signal transduction and apoptosis. The coordinated assembly and disassembly of actin filaments is controlled by a multitude of proteins (ABPs) in the cell. LÄS MER

  3. 7. Visualizing structural dynamics: from small molecules to membrane proteins

    Författare :Magnus Andersson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; membrane protein; bacteriorhodopsin; proteorhodopsin; halorhodopsin; structural dynamics; time-resolved X-ray scattering;

    Sammanfattning : To fully understand the mechanism of a chemical reaction, it is important to characterize the rapid structural dynamics of transient chemical species as the reaction propagates. Since chemical processes are heavily influenced by the solvent in which they occur, the interaction with the surrounding solution also needs to be elucidated. LÄS MER

  4. 8. Transthyretin and the transthyretin-related protein: A structural study

    Författare :Erik Lundberg; A. Elisabeth Sauer-Eriksson; Lennart Sjölin; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Transthyretin; Transthyretin-related protein; X-ray crystallography; Protein structure; Amyloidosis; Structural biology; Strukturbiologi;

    Sammanfattning : Transthyretin (TTR) is one of several proteins involved in amyloid disease in humans. Unknown conformational changes of the native state of TTR result in aggregation of TTR molecules into amyloid fibrils, which accumulate in extracellular tissues. This may result in different clinical symptoms, e.g. LÄS MER

  5. 9. Structural Studies on PP2A and Methods in Protein Production

    Författare :Auður Magnúsdóttir; Pär Nordlund; Herman Van Tilbeurgh; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PP2A; PTPA; B56γ; Protein Production; Structural biology; Strukturbiologi; biokemi; Biochemistry;

    Sammanfattning : PP2A is a major phosphatase in the cell that participates in multiple cell signaling pathways. It is a heterotrimer of a core dimer and variable regulatory subunits. Details of its structure, function and regulation are slowly emerging. Here, the structure of two regulators of PP2A are de-scribed; PTPA and B56γ. LÄS MER

  7. 10. Structural basis for metalloprotein catalysis : Characterization of Mycobacterium tuberculosis phosphatidylinositol phosphate synthase PgsA1 and Bacillus anthracis ribonucleotide reductase R2

    Författare :Kristīne Grāve; Martin Högbom; Susanna Törnroth-Horsefield; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; biokemi;

    Sammanfattning : About a third of all proteins need to associate with a particular metal ion or metallo-inorganic cofactor to function. This interplay expands the catalytic repertoire of enzymes and reflects the adaption of these catalytic macromolecules to the environments they have evolved in. LÄS MER