Sökning: "Structural"

Visar resultat 16 - 20 av 5826 avhandlingar innehållade ordet Structural.

  1. 16. Structural Studies of Glutamine Synthetases – Towards the Development of Novel Antitubercular Agents

    Författare :Wojciech W. Krajewski; Sherry L. Mowbray; Torsten Unge; Thomas C. Terwilliger; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Structural biology; Strukturbiologi;

    Sammanfattning : Glutamine synthetase (GS) plays an important role in nitrogen metabolism, where it catalyzes the ATP-dependent condensation of glutamate and ammonia to yield glutamine. Recent studies showed the importance of M. tuberculosis GS (MtGS) for growth and survival of the bacterium, and demonstrated its potential as a drug target. LÄS MER

  3. 17. Structural assessment procedures for existing concrete bridges : Experiences from failure tests of the Kiruna Bridge

    Författare :Niklas Bagge; Björn Täljsten; Paulo Cruz; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Anchorage; carbon fibre reinforced polymers; concrete; existing bridges; finite element analysis; flexure; full-scale test; load-carrying capacity; residual prestress force; punching; safety verification; shear; structural assessment; structural behaviour; Structural Engineering; Konstruktionsteknik;

    Sammanfattning : Assessing existing bridges is an important task in the sustainable management ofinfrastructure. In practice, structural bridge assessments are usually conducted usingtraditional and standardised methods, despite knowledge that these methods oftenprovide conservative estimates. LÄS MER

  4. 18. Structural biology studies of thylakoid lumen proteins required for photosystem II assembly and function

    Författare :Roland Locmelis; Uwe Sauer; Wolfgang Schröder; Inger Andersson; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; structural biology; x-ray crystallography; cloning; protein expression; HCF136; LPA19; MPH2; Prx6; photosynthesis; thylakoid lumen PSII;

    Sammanfattning : Little is known about the structures and functions of thylakoid lumen proteins. However, some of these proteins have an essential role in photosynthesis. LÄS MER

  5. 19. Structural studies of sugar binding proteins

    Författare :Sanjeewani Sooriyaarachchi; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Binding proteins, which are themselves non-enzymatic, play an important role in enzymatic reactions as well as non-enzymatic processes by providing a binding platform for the specific recognition of particular molecules. For example, periplasmic binding proteins play a vital role in nutrient uptake in Gram-negative bacteria. LÄS MER

  7. 20. Evasion and Attack: Structural Studies of a Bacterial Albumin-binding Protein and of a Cephalosporin Biosynthetic Enzyme

    Författare :Sara Lejon; Janos Hajdu; Karin Valegård; Martin Noble; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; human serum albumin; GA module; albumin-binding; Finegoldia magna; deacetylcephalosporin C acetyltransferase; cephalosporin C; antibiotic; beta-lactam; biosynthesis; Acremonium chrysogenum; X-ray crystallography; Structural biology; Strukturbiologi;

    Sammanfattning : This thesis describes the crystal structures of two proteins in the context of combatting bacterial infections. The GA module is a bacterial albumin-binding domain from a surface protein expressed by pathogenic strains of the human commensal bacterium Finegoldia magna. LÄS MER