Sökning: "Structural isomers"

Visar resultat 11 - 15 av 24 avhandlingar innehållade orden Structural isomers.

  1. 11. Detection and Structure Elucidation of Drug Metabolites in Biological Samples using HPLC-MS/MS Techniques

    Författare :Annica Tevell Åberg; Mikael Hedeland; Ulf Bondesson; Mario Thevis; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; Farmaceutisk kemi; analytisk farmaceutisk kemi; Analytical Pharmaceutical Chemistry;

    Sammanfattning : This thesis describes the structure elucidation of drug metabolites in biological samples by the use of high performance liquid chromatography (HPLC) atmospheric pressure ionization (API) tandem mass spectrometry (MS/MS). Due to their different advantages, various mass analyzers have been used in the different experiments. LÄS MER

  3. 12. Collision- and photon-induced dynamics of complex molecular ions in the gas phase

    Författare :Linda Giacomozzi; Henning Zettergren; Jason Greenwood; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PAHs; Porphyrins; Adenine; Flavins; Biomolecules; Collisions; Experiments; Reactions; Non-Statistical Fragmentation; Molecular Dynamics; Photon-Induced Fragmentation; Luminescence; Photoisomerization; Proton Transfer; fysik; Physics;

    Sammanfattning : In this thesis, I report experiments probing collision- and photon-induced molecular dynamics in the gas phase. Excited molecules formed in such interactions may relax by emitting electrons or photons, isomerization or fragmentation. LÄS MER

  4. 13. Moleculary imprinted micro- and nanoparticles for cancer associated glycan motifs

    Författare :Liliia Mavliutova; Börje Sellergren; Michael Whitcombe; Malmö universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Moleculary imprinted polymer; sialic acid; glycan recognition; synthetic receptor;

    Sammanfattning : Sialic acids are an important family of monosaccharides that are typically found as terminal moieties of glycans. Aberrant sialylation has been proven to correlate with various diseases including cancer. Glycosylation analysis is complex due to high diversityof the glycan isomers and their low abundance. LÄS MER

  5. 14. 5-Aminolevulinic acid and derivatives thereof : properties, lipid permeability and enzymatic reactions

    Författare :Edvin Erdtman; Leif Eriksson; Tore Brinck; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; 5-Aminolevulinic acid; tautomerization; PDT; DFT; MM; QM MM; Porphobilinogen synthase; Uroporphyrinogen III decarboxylase; membrane penetration; enzyme mechanism; Biophysical chemistry; Biofysikalisk kemi; Quantum chemistry; Kvantkemi; Theoretical chemistry; Teoretisk kemi; Fysikalisk kemi; Physical Chemistry; Biochemistry; Biokemi;

    Sammanfattning : 5-aminolevulinic acid (5-ALA) and derivatives thereof are widely usedprodrugs in treatment of pre-malignant skin diseases of the cancer treatmentmethod photodynamic therapy (PDT). The target molecule in 5-ALAPDTis protoporphyrin IX (PpIX), which is synthesized endogenously from5-ALA via the heme pathway in the cell. LÄS MER

  7. 15. Modelling precipitation and surface complexation reactions in systems with Goethite, Cu(II) and Oxyanions Containing As(V) or P(V)

    Författare :Hanna Nelson; Lars Lövgren; Staffan Sjöberg; Per Persson; M. Clara F. Magalhaes; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The aqueous solubility of oxyanion (e.g. phosphates and arsenates), and thereby their mobility, bioavailability (phosphates) and toxicity (arsenates), in soils and sediments is dependent upon their chemical speciation. In complex, multicomponent systems, equilibrium modelling can be a useful tool to predict chemical speciation. LÄS MER