Sökning: "Streptolysin"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet Streptolysin.

1. 1. Immunoglobulin-binding bacterial surface proteins; biomedical tools and virulence factors

   Författare :Britt-Marie Kihlberg; Infektionsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Phagocytosis; M-like protein; M protein; Protein L; Protein G; Ig-binding; Streptococcus pyogenes; Fc Receptors; mykologi; virologi; bakteriologi; Mikrobiologi; mycology; virology; bacteriology; Microbiology; Cysteine proteinase; Streptolysin;

   Sammanfattning : Many bacteria express immunoglobulin(Ig)-binding proteins that interact with Ig in a non-immune manner. Several of these Ig-binding bacterial proteins have been well characterized and are widely used as reagents for analysis and purification of Ig's. LÄS MER

3. 2. Interactions between Streptococcus pyogenes and the human immune defence

   Författare :Maria E Nilsson; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; M protein; Streptococcus pyogenes; Streptolysin O; The complement system; Neutrophils; Biomedical sciences; Biomedicinska vetenskaper; General biomedical sciences; Biomedicinska vetenskaper allmänt ; Microbiology; transplantation; Immunology; serology; mykologi; virologi; bakteriologi; Mikrobiologi; mycology; virology; Immunologi; serologi; Infections; Infektioner; Clinical biology; Klinisk biologi; bacteriology;

   Sammanfattning : Streptococcus pyogenes is an important human pathogen frequently colonizing the throat and skin of humans. To facilitate colonization and spread and to avoid the host immune defence, streptococci are endowed with a variety of virulence factors, two of which are investigated in this thesis namely streptolysin O (SLO) and M protein. LÄS MER

4. 3. On the effects of Streptococcal NAD+-glycohydrolase and Streptolysin O on macrophages

   Författare :Elsa Westerlund; Värd-patogeninteraktioner; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Innate immunity; macrophage; Streptococcus pyogenes; IL-1beta; Nad -glycohydrolase;

   Sammanfattning : SummaryThe human pathogen Streptococcus pyogenes (GAS) causes both superficial infections, such as strep throat, and invasive infections, such as necrotizing fasciitis, and is responsible for about half a million deaths each year. The number of GAS infections have increased since the 1980’s, due to the emergence of a M1T1 strain that has become widely disseminated. LÄS MER

5. 4. Regulation of inflammasomes by host- and pathogen-derived factors

   Författare :Dora Hancz; Värd-patogeninteraktioner; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Innate Immunity; pattern recognition receptors; inflammasome; Streptococcus pyogenes;

   Sammanfattning : The term inflammasome was first coined in 2002 and describes an intracellular multiprotein complex mediating inflammation by inducing the release of pro-inflammatory cytokines (IL-1β and IL-18) and a lytic form of cell death called pyroptosis. Since then, an impressive amount of research has revealed many details about the mechanisms of inflammasome activation as well as the functional relevance of inflammasome activation in different contexts. LÄS MER

7. 5. Influence of MHC class I peptide interaction on antigen presentation in normal and malignant cells

   Författare :Qian-Jin Zhang; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Cytotoxic T lymphocytes; Natural Killer cells; Epstein-Barr virus; MHC class I; class I binding motifs; T cell receptor; antigen presentation; immunodominance;

   Sammanfattning : The presentation of MHC class I peptide complexes in normal and malignant cells was studied. An HLA A11 binding motif was defined by comparing synthetic peptide analogues of a known cytotoxic T Iymphocyte (CTL) target epitope for induction of surface A11 expression and triggering of cytotoxic activity. LÄS MER