Sökning: "Streptococcus pyogenes"

Visar resultat 21 - 25 av 94 avhandlingar innehållade orden Streptococcus pyogenes.

1. 21. Evolutionary and functional studies of protein H: a surface molecule of Streptococcus pyogenes

   Författare :Inga-Maria Frick; Infektionsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intracellular transportation; adhesion; aggregation; FNIII domain; albumin-binding; M-like protein; convergent evolution; protein G; Streptococcus pyogenes; IgG-binding; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

   Sammanfattning : Several bacterial species express surface proteins with affinity for the Fc part of human IgG. This thesis describes evolutionary and functional studies of protein H, an IgGFc-binding surface protein of the human pathogen Streptococcus pyogenes. LÄS MER

3. 22. Phagocytosis by neutrophils - studies on phagosome dynamics and membrane traffic modulation by Streptococcus pyogenes

   Författare :Pontus Nordenfelt; Infektionsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; fluorescence microscopy; membrane traffic; neutrophil; Streptococcus pyogenes; phagosome; phagocytosis;

   Sammanfattning : Neutrophils are our most numerous and deadly white blood cells and without them we would succumb quickly to infections by pathogens. The main mechanism that the neutrophils employ for our protection is phagocytosis, where they eat and enclose their target inside a membrane-bound organelle, the phagosome. LÄS MER

4. 23. Streptococcus pyogenes : life within the macrophage

   Författare :Erika Hertzén; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Streptococcus pyogenes is a versatile human pathogen causing a wide array of diseases ranging from uncomplicated throat and skin infections to invasive life- threatening diseases with a mortality rate of up to 60%. It is ranked number nine on the list of worst infectious diseases world wide, causing 500 000 deaths yearly. LÄS MER

5. 24. Interactions between Streptococcus pyogenes and the human immune system, with special reference to C4b-binding protein

   Författare :Anette Thern; Avdelningen för medicinsk mikrobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; Phagocytosis; M-proteins; M-like proteins; Bovine C4b-binding protein; Streptococcus pyogenes; Human C4b-binding protein; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

   Sammanfattning : The ability of many pathogenic microorganisms to cause infection is dependent on their ability to evade attack by the complement system of the host. One mechanism by which microorganisms may avoid complement attack is to bind complement inhibitory molecules present in the host. LÄS MER

7. 25. Studies on cell wall-attached proteins of Streptococcus pyogenes

   Författare :Magnus Rasmussen; Infektionsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; insertion sequence; phase variation; collagen-like; alpha2-macroglobulin; pattern; virulence; surface protein; Stretococcus pyogenes; cell wall-attached protein; Clinical biology; Klinisk biologi;

   Sammanfattning : Cell wall-attached proteins (CWPs) are important for the virulence of Gram-positive bacteria, but are also targets for the host immune system. CWPs have a conserved COOH-terminal region, responsible for cell wall-sorting. A pattern based on this conserved region was developed. LÄS MER