Sökning: "Streptococcal M proteins"
Visar resultat 1 - 5 av 22 avhandlingar innehållade orden Streptococcal M proteins.
1. Molecular studies on streptococcal surface proteins
Sammanfattning : Streptococcus agalactiae and Streptococcus pyogenes are two related human pathogens causing different diseases. This thesis focuses on a number of surface proteins expressed by S. agalactiae and S. pyogenes and, more specifically, the molecular and biological characterization of these proteins. LÄS MER
2. Interactions between streptococcal M proteins and human plasma proteins
Sammanfattning : Streptococcus pyogenes is a common human pathogen, which causes a variety of diseases. A major virulence factor of S. pyogenes is the surface-associated M protein, which mediates resistance to phagocytosis. Several studies indicate that M proteins inhibit complement deposition and thereby phagocytosis. LÄS MER
3. Streptococcal M protein and human C4BP
Sammanfattning : Antigenic variation of surface proteins allows microorganisms to evade the immune system of the infected host. This phenomenon represents an apparent paradox, because the variable protein must retain an important function, while its antigenic properties vary extensively. LÄS MER
4. Temperature-dependent structure and function of group A streptococcal M proteins
Sammanfattning : Temperature-dependent structure and function of group A streptococcal M proteins.This thesis describes the temperature-dependent structure of the members in the group A streptococcal M protein family. M proteins are cell-surface proteins that are important for the bacterial virulence and bind to a diverse set of human plasma proteins. LÄS MER
5. Studies on streptococcal M proteins. Interactions with IgA and human complement regulators
Sammanfattning : The human pathogenic bacterium Streptococcus pyogenes (group A Streptococcus) expresses several different virulence factors. Of these, the M protein is regarded as one of the most important, because it confers resistance to phagocytosis, allowing the bacterium to multiply in blood. LÄS MER