Sökning: "Strålningsfysik"

Visar resultat 1 - 5 av 160 avhandlingar innehållade ordet Strålningsfysik.

  1. 1. Microdosimetric description of beam quality and biological effectiveness in radiation therapy

    Författare :Aris Tilikidis; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Dose-response relationship; radiation; Radiotherapy: adverse effects; Radiotherapy dosage; Radiotherapy planning; computer-assisted; Strålningsfysik; Medicin Radioterapi;

    Sammanfattning : .... LÄS MER

  3. 2. Improved dose response modeling for normal tissue damage and therapy optimization

    Författare :Magdalena Adamus-Górka; Bengt K. Lind; Anders Brahme; Panayiotis Mavroidis; Randall K. Ten Haken; Stockholms universitet; []
    Nyckelord :Normal tissue complications; radiobiological models; dose-response; volume effect; spinal cord; effective FSU size; medicinsk strålningsfysik; Medical Radiation Physics;

    Sammanfattning : The present thesis is focused on the development and application of dose response models for radiation therapy. Radiobiological models of tissue response to radiation are an integral part of the radiotherapeutic process and a powerful tool to optimize tumor control and minimize damage to healthy tissues for use in clinical trials. LÄS MER

  4. 3. Development of tissue-equivalent CVD-diamond radiation detectors with small interface effects

    Författare :Bartosz Górka; Bo Nilsson; José M. Fernández-Varea; Anders Brahme; Hugo Palmans; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; CVD-diamond detector; tissue-equivalent encapsulation; dosimetry; Monte Carlo simulation; Physics; Fysik; medicinsk strålningsfysik; Medical Radiation Physics;

    Sammanfattning : Due to its close tissue-equivalence, high radiation sensitivity, dose and dose-rate linearity, diamond is a very promising detector for radiation therapy applications. The present thesis focuses on the development of a chemical vapour deposited (CVD) diamond detector with special attention on the arrangement of the electrodes and encapsulation having minimal influence on the measured signal. LÄS MER

  5. 4. Absorbed dose and biological effect in light ion therapy

    Författare :Malin Hollmark; Irena Gudowska; Oliver Jäkel; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Light ion therapy; absorbed dose calculation; analytical pencil beam model; Monte Carlo; radiobiological modeling; Radiological physics; Radiofysik; medicinsk strålningsfysik; Medical Radiation Physics;

    Sammanfattning : Radiation therapy with light ions improves treatment outcome for a number of tumor types. The advantageous dose distributions of light ion beams en-able exceptional target conformity, which assures high dose delivery to the tumor while minimizing the dose to surrounding normal tissues. LÄS MER

  7. 5. Development of analytical transport methods for biologically optimized light ion therapy

    Författare :Johanna Kempe; Anders Brahme; Irena Gudowska; Naruhiri Matsufuji; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Radiotherapy; radiation quality; energy-range relations; light ion transport; pencil beam; Monte Carlo; Physics; Fysik; medicinsk strålningsfysik; Medical Radiation Physics;

    Sammanfattning : A general objective in the treatment of cancer is to eradicate the tumour cells without inducing severe complications in healthy normal tissue. The use of light ions for radiation therapy increases the possibility to deliver tumour suicidal doses with very low probability of normal tissue injury, not least in cases where the target is unresectable, radioresistant and located to near organs at risk. LÄS MER