Sökning: "Stockholms Universitet Institutionen För Biokemi Och Biofysik"

Visar resultat 1 - 5 av 329 avhandlingar innehållade orden Stockholms Universitet Institutionen För Biokemi Och Biofysik.

  1. 1. Large-scale prediction of protein subcellular localization : sequence-based methods and applications

    Författare :Olof Emanuelsson; Alfonso Valencia; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Biophysics; Biofysik; Biochemistry; Biokemi; Biophysics; biofysik;

    Sammanfattning : .... LÄS MER

  3. 2. Exploring the Interplay of Lipids and Membrane Proteins

    Författare :Candan Ariöz; Åke Wieslander; Daniel O. Daley; Malcolm East; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Membrane lipids; membrane proteins; anionic lipids; membrane remodeling; intracellular vesicles; model membrane systems; glycosyltransferase; Escherichia coli; lipid composition; fatty acid modification; membrane curvature; bacterial homeoviscous adaptation; Biochemistry; biokemi;

    Sammanfattning : The interplay between lipids and membrane proteins is known to affect membrane protein topology and thus have significant effect (control) on their functions. In this PhD thesis, the influence of lipids on the membrane protein function was studied using three different membrane protein models. LÄS MER

  4. 3. Dynamics of peptide chains during co-translational translocation, membrane integration & domain folding

    Författare :Rickard Hedman; Gunnar von Heijne; Daniel N. Wilson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ribosome; membrane integration; translocation; folding; arrest peptide; SecM; Biochemistry; biokemi;

    Sammanfattning : The biosynthesis of proteins occurs at the ribosomes, where amino acids are linked together into linear chains. Nascent protein chains may undergo several different processes during their synthesis. Some proteins begin to fold, while others interact with chaperones, targeting factors or processing enzymes. LÄS MER

  5. 4. The molecular basis for substrate recognition and gating in sugar transporters

    Författare :Sarah McComas; David Drew; Philip Biggin; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; membrane transport; sugar transporter; simulations; lipids; antimalarial drugs; biokemi; Biochemistry;

    Sammanfattning : Sugar is a vital sustenance for most forms of life. For a cell to take up sugar, specialized transport proteins embedded into the membrane bilayer known as sugar porters, are required. LÄS MER

  7. 5. Structural transitions of proton-gated ion channels : Involving pH sensing, heterogeneity and lipid interactions

    Författare :Urška Rovšnik; Erik Lindahl; Hugues Nury; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ion channels; cryo-electron microscopy; pH gating; simulations; structure-function relationship; GLIC; DeCLIC; biokemi; Biochemistry;

    Sammanfattning : Studying protein structure and function involves analyzing the relationship between a protein's three-dimensional assembly and its dynamic biochemical activity. The superfamily of pentameric ligand-gated ion channels (pLGICs) constitutes a classic yet illuminating experimental system for structure-function studies. LÄS MER