Sökning: "Stina Garvin"

Hittade 3 avhandlingar innehållade orden Stina Garvin.

  1. 1. Effects of sex steroids and tamoxifen on VEGF in the breast

    Författare :Stina Garvin; Charlotta Dabrosin; Lars Holmgren; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiogenesis; breast cancer; estradiol; MCF-7; microdialysis; nude mice; progesterone; sVEGFR-1; VEGFR-2; Oncology; Onkologi;

    Sammanfattning : Sex steroid exposure constitutes a risk factor for breast cancer, but little is known about the effects of sex steroids on factors mediating angiogenesis, the development of new blood vessels, in normal and malignant breast tissue. In this thesis we have investigated the effects of estradiol, progesterone, and the nonsteroidal anti-estrogen tamoxifen on vascular endothelial growth factor (VEGF) and its receptors (VEGFR-1 and VEGFR-2) in normal human breast tissue, endothelial cells, and breast cancer. LÄS MER

  3. 2. Generalisation and reliability of deep learning for digital pathology in a clinical setting

    Författare :Milda Pocevičiūtė; Claes Lundström; Stina Garvin; Gabriel Eilertsen; Nasir Rajpoot; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Deep learning; Digital pathology; Generalisation; Uncertainty estimation; Anomaly detection; Data distribution shift;

    Sammanfattning : Deep learning (DL) is a subfield of artificial intelligence (AI) focused on developing algorithms that learn from data to perform some tasks that can aid humans in their daily life or work assignments. Research demonstrates the potential of DL in supporting pathologists with routine tasks like detecting breast cancer metastases and grading prostate cancer. LÄS MER

  4. 3. The impact of Survivin, WRAP53β, and Hypoxia on treatment response in Head and Neck Cancer

    Författare :Katharina Tiefenböck-Hansson; Karin Roberg; Lovisa Farnebo; Stina Garvin; Eva Brun; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Squamous cell carcinoma (SCC) is the most common histological type of cancer in the head and neck region and arises in the epithelial mucosa of the upper aerodigestive tract. Approximately one and a half million people are living with the diagnosis. LÄS MER