Sökning: "Sterol"

Visar resultat 6 - 10 av 52 avhandlingar innehållade ordet Sterol.

  1. 6. Analysis of sterol metabolism in the pathogenic oomycetes Saprolegnia parasitica and Phytophthora infestans

    Författare :Paul Dahlin; Vincent Bulone; Lisbeth Jonsson; Katharina Pawlowski; Lauren Mckee; Sophia Ekengren; Folke Sitbon; Steven Kelly; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Plant Physiology; växtfysiologi;

    Sammanfattning : The primary objective of this thesis was to investigate the sterol metabolism of two pathogenic oomycetes, specifically the processes of sterol synthesis and sterol acquisition in the fish pathogen Saprolegnia parasitica (Saprolegniales) and the plant pathogen Phytophthora infestans (Peronosporales). Furthermore, the effects of steroidal glycoalkaloids from Solanaceous plants, on P. LÄS MER

  3. 7. Studies of sterol 12alpha-hydroxylase (CYP8B1) : distribution and role for cholesterol homeostasis and gallstone formation

    Författare :Jin Wang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :CYP8B1; CY7P7A1; bile acid; cholesterol homeostasis; gallstone; nuclear receptor; cellular distribution; cholesterol hypersecretion; ABCG5 G8; SREBP2; cholesterol absorption; diabetes mellitus; anti-atherogenesis;

    Sammanfattning : Bile acids are essential physiological molecules which carry out multiple functions such as facilitating the absorption of dietary lipids and regulating the metabolism of cholesterol and bile acids. The formation of bile represents the major route for elimination of excess cholesterol, either by conversion of cholesterol into bile acids or excretion of intact cholesterol in mixed micelles. LÄS MER

  4. 8. Regulation of sterol and glycoalkaloid biosynthesis in potato (Solanum tuberosum L.) : identification of key genes and enzymatic steps

    Författare :Nurun Nahar; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Steroidal glycoalkaloids (SGA) are toxic secondary metabolites present in some members of the Solanaceae family, including potato and tomato. The SGA level in tubers of potato (Solanum tuberosum L.) depends on genetic factors, but can also increase in response to e.g. LÄS MER

  5. 9. Effect of wounding and light exposure on sterol, glycoalkaloid, and calystegine levels in potato plants (Solanum tuberosum L. group Tuberosum)

    Författare :Usman Arif; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Steroidal glycoalkaloids (SGA) are neurotoxic substances that are present in some members of the Solanaceae family, including crop species like potato (Solanum tuberosum L.) and tomato. LÄS MER

  7. 10. Studies on human sterol 27-hydroxylase with emphasis on its mechanism of regulation and metabolic consequences of a deficient enzyme

    Författare :Magnus Hansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Sterol 27-hydroxylase (CYP27A1) is a mitochondrial cytochrome P-450 enzyme present in most animal cells. In hepatocytes, CYP27A1 has an important role in connection with biosynthesis of bile acids from cholesterol. LÄS MER