Sökning: "Sterol"

Visar resultat 1 - 5 av 49 avhandlingar innehållade ordet Sterol.

  1. 1. Partitioning of Drugs and Lignin Precursor Models into Artificial Membranes

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Elisabet Boija; Uppsala universitet.; [2006]
    Nyckelord :Biochemistry; Bilayer disk; Capillary electrophoresis; Detergent; Drug; Electrostatic interaction; Hydrophobic interaction; Immobilized liposome chromatography; Lignin; Lignin precursor model; Liposome; Membrane model; Octanol water partitioning; Partitioning; Phospholipid; Phospholipid bilayer; Sterol; Biokemi;

    Sammanfattning : The main aim of this thesis was to characterize membrane-solute interactions using artificial membranes in immobilized liposome chromatography or capillary electrophoresis. The partitioning of a solute into a cell membrane is an essential step in diffusion across the membrane. LÄS MER

  2. 2. Studies on sterol 27-hydroxylase (CYP27A1)

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Laboratory Medicine

    Författare :Sara von Bahr; Karolinska Institutet.; Karolinska Institutet.; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Human sterol 27-hydroxylase (CYP27A1) has been studied in the present thesis with focus on substrate specificity and possible role of the enzyme for prevention of accumulation of cholesterol and cholestanol in tissues. Attempts have been made to evaluate a metabolic pathway to bile acids in human primary hepatocytes that starts with a 27-hydroxylation of cholesterol catalyzed by CYP27A1. LÄS MER

  3. 3. Phytosterols. Effect of intake on cholesterol absorption and colorectal cancer risk

    Detta är en avhandling från Göteborg

    Författare :Lena Normén; Göteborgs universitet.; Gothenburg University.; [2001]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; phytosterols; phytostanols; soy sterols; sitostanol; ester; gas-liquid chromatography; GLC; cholesterol absorption; sterol excretion; fruit; vegetables; cereals; colon cancer; rectal cancer; dietary fiber;

    Sammanfattning : Phytosterols are lipid components of all food items of plant origin. They are effective in decreasing plasma cholesterol concentrations, but have also been suggested to protect against colorectal cancer. LÄS MER

  4. 4. Plant sterol metabolism with emphasis on glycoalkaloid biosynthesis in potato

    Detta är en avhandling från Göteborg

    Författare :Lisa Beste; Sveriges lantbruksuniversitet.; [2007]
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  5. 5. Studies on the transcriptional regulation of sterol 12alpha-hydroxylase (CYP8B1)

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Laboratory Sciences and Technology

    Författare :Yizeng Yang; Karolinska Institutet.; Karolinska Institutet.; [2002]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bile acids; CYP8B1; CYP7A1; transcription; nuclear receptor; PPAR-alpha; HNF4-alpha; FTF; SREBP; thyroid hormones.;

    Sammanfattning : The conversion of cholesterol into bile acids is mainly via two pathways, which are initiated by CYP7A1 and CYP27A1 respectedly. CYP8B1, a microsomal P450 cytochrome, hydroxylates of the steroid nucleus at the C-12alpha position to form 7alpha, 12alpha-dihydroxy-4-cholesten-3-one, a facultative precursor of CA. LÄS MER