Sökning: "Stephan Grzesiek"

Hittade 1 avhandling innehållade orden Stephan Grzesiek.

1. 1. Structure and Dynamics of the Hepatitis B Virus Encapsidation Signal Revealed by NMR Spectroscopy

   Författare :Sara Flodell; Stephan Grzesiek; Umeå universitet; []
   Nyckelord :HBV; RNA; isotope labelling; NMR; structure determination; medicinsk biokemi; Medical Biochemistry;

   Sammanfattning : This thesis describes the study of the three-dimensional structure and dynamics of the hepatitis B virus (HBV) encapsidation signal, epsilon, by means of nuclear magnetic resonance (NMR) and mutational data. HBV replicates by reverse transcription of an RNA pregenome into the viral DNA genome, which becomes enclosed in viral particles (encapsidation). LÄS MER