Sökning: "Sten Nilsson"
Visar resultat 21 - 25 av 28 avhandlingar innehållade orden Sten Nilsson.
21. Affibody Molecules for HER3-targeted Theranostics of Malignant Tumours
Sammanfattning : The HER3 receptor plays a strong role in disease progression and resistance to therapies in several cancer types. Due to its endogenous expression and low overexpression in malignant tumours, it is a particularly challenging target. LÄS MER
22. The gastrointestinal tract in cardiac anaesthesia and intensive care : Clinical and experimental studies
Sammanfattning : Gastrointestinal (GI) complications after cardiac surgery have a substantial impact on outcome. The aims were to investigate the frequency of, and methods for detecting, GI dysfunction after cardiac surgery and its relation to outcome, and the impact of vasoactive drugs on the GI tract in experimental cardiogenic shock. LÄS MER
23. Experimental Diagnostics and Therapeutics of Invasive Urinary Bladder Cancer
Sammanfattning : The two purposes of this thesis were to evaluate new diagnostic techniques of lymphnode staging in invasive bladder cancer and to evaluate the results of neoadjuvant chemotherapy in invasive bladder cancer.Sentinel node detection was performed in 13 patients in preparation for radical cystectomy. LÄS MER
24. Affibody Molecules for PET Imaging
Sammanfattning : Optimization of Affibody molecules would allow for high contrast imaging of cancer associated surface receptors using molecular imaging. The primary aim of the thesis was to develop Affibody-based PET imaging agents to provide the highest possible sensitivity of RTK detection in vivo. LÄS MER
25. Mathematical Modelling of Cerebral Metabolism : From Ion Channels to Metabolic Fluxes
Sammanfattning : The brain is the most metabolically active organ in the human body and therefore rely on a continuous supply of oxygen and glucose. Neuronal stimulation in specific regions of the leads to the firing of action potentials, a process facilitated by voltage-gated ion channels in the neurons’ cell membranes. LÄS MER