Sökning: "Stefan Ulvenlund"

Hittade 3 avhandlingar innehållade orden Stefan Ulvenlund.

  1. 1. Prolonged Drug Release from Gels, using Catanionic Mixtures

    Författare :Tobias Bramer; Katarina Edsman; Per Hansson; Stefan Ulvenlund; Uppsala universitet; []
    Nyckelord :Pharmaceutics; gel; catanionic; vesicle; micelle; controlled release; diffusion; surfactant; drug delivery; Galenisk farmaci;

    Sammanfattning : The use of catanionic drug-surfactant mixtures was proven to be an efficient novel method of obtaining prolonged drug release from gels. It was shown that various commonly used drug compounds are able to form catanionic mixtures together with oppositely charged surfactants. LÄS MER

  3. 2. Catanionic Aggregates in Gels : Prolonged Drug Release and Potential Implications for Topical Use

    Författare :Noel Dew; Erik Björk; Stefan Ulvenlund; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; Galenisk farmaci; Galenisk farmaci; Pharmaceutics;

    Sammanfattning : Gels are popular dosage forms.  This topical dosage form may be advantageous compared to oral or parenteral dosage forms. Favorable rheological or bioadhesive properties of gels might provide extended contact times at the site of administration compared to aqueous solutions. LÄS MER

  4. 3. On the chemical and processing stability of pharmaceutical solids : Solid form dependent water presenting capacity and process induced solid form transformation

    Författare :Mina Heidarian Höckerfelt; Göran Alderborn; Stefan Ulvenlund; Uppsala universitet; []
    Nyckelord :;

    Sammanfattning : There is a need for improving our knowledge and understanding about formation mechanisms and nature of amorphous state in order to prevent the unintended presence of disorder in solid pharmaceutical products and reduce the related stability issues. The suggested theory that water binding capacity of amorphous cellulose affects the chemical stability of hydrolysis sensitive drugs in formulations with cellulose based excipients needs a clarification and water-cellulose interaction profiles need to be examined. LÄS MER