Sökning: "Stefan Ståhl"
Visar resultat 11 - 15 av 19 avhandlingar innehållade orden Stefan Ståhl.
11. Staphylococcal surface display in directed evolution
Sammanfattning : Engineered affinity proteins have together with naturally derived antibodies becomeindispensable tools in many areas of life-science and with the increasing number ofapplications, the need for high-throughput methods for generation of such different affinityproteins is evident. Today, combinatorial protein engineering is the most successful strategy toisolate novel non-immunoglobulin affinity proteins. LÄS MER
12. Engineering of Affibody molecules targeting the Alzheimer’s-related amyloid β peptide
Sammanfattning : .... LÄS MER
13. Tumor targeted delivery of cytotoxic payloads using affibody molecules and ABD-derived affinity proteins
Sammanfattning : Cancer treatment cost billions of dollars every year, but the mortality rate is still high. An ideal treatment is the so-called “magic bullets” that recognize and kill tumor cells while leaving normal cells untouched. LÄS MER
14. Staphylococcal surface display for protein engineering and characterization
Sammanfattning : Even though our understanding of mechanisms such as protein folding and molecular recognition is relatively poor, antibodies and alternative affinity proteins with entirely novel functions are today generated in a routine manner. The reason for this success is an engineering approach generally known as directed evolution. LÄS MER
15. Generation and characterization of Affibody molecules targeting HER3
Sammanfattning : In the field of oncology, the ability to target specific tumor cells using highly selective targeting molecules is an attractive and emerging concept. In this context, the epidermal growth factor receptor HER3 has proven central to the biology behind many different human cancers and inhibition of the signaling mediated by this receptor could provide antitumoral effects. LÄS MER
