Sökning: "Statin"
Visar resultat 16 - 20 av 66 avhandlingar innehållade ordet Statin.
16. Posttransplantational bone disease : the effect of immunosuppressive drugs on bone : clinical and experimental studies
Sammanfattning : Osteoporosis and pathologic fractures are frequent complications ill patients with end-stage liver or kidney diseases. Although successful transplantation eliminates some factors related to poor organ function, all increased incidence of pathologic fractures was reported ill the early post-transplant period in spite of normalization of the allograft function. LÄS MER
17. Power of the Pill : Views about Cardiovascular Risk and the Risk-reducing Effect of Statins
Sammanfattning : Medical treatments with statins are prescribed to patients with increased risk of cardiovascular events. The benefits from statin treatment are well documented in clinical trials, but long-term adherence in patients is low, indicating that patients have an uncertainty about the necessity and benefits of treatment. LÄS MER
18. Inhibition of the mevalonate pathway in C. elegans: Consequences and implications
Sammanfattning : The mevalonate pathway in human is responsible for the synthesis of cholesterol and other important biomolecules such as coenzyme Q (a component of the electron transport chain in mitochondria), dolichols (important for N-linked glycosylation of proteins) and isoprenoids (important for the membrane association of small GTPases). This thesis concerns novel findings about the effect of statin on the mevalonate pathway using C. LÄS MER
19. Cholesterol metabolism in breast cancer: Prognostic factors and optimizing treatment
Sammanfattning : AbstractBreast cancer (BC) is the most common cancer among women in Sweden and worldwide. Adjuvant endocrine therapies are effective, yet 20-30% patients experience disease relapse. Altered cholesterol metabolism is an emerging hallmark of breast cancer proliferation and endocrine therapy resistance. LÄS MER
20. Common medications in the risk and prognosis of lymphoid neoplasms and epidemiology of primary CNS lymphoma
Sammanfattning : Lymphoid neoplasms are malignancies arising from the lymphocyte, and include lymphoma subtypes, chronic lymphocytic leukemia (CLL) and multiple myeloma (MM). It is a heterogenous group of diseases, with different molecular pathogenesis, clinical characteristics, treatments and outcome. LÄS MER